Identification and characterisation of novel RNAs involved in cardiovascular cell (de)differentiation.
Identification and characterisation of novel RNAs involved in cardiovascular cell (de)differentiation.
批准号:
nhmrc : 1051485
负责人:
A/Pr Jody Haigh
金额:
$42.19万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2013
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2013-01-01 至 2016-12-31
中文摘要
最近的几项突破让我们意识到,细胞发育具有很大的可塑性,我们现在可以利用这种可塑性来创造干细胞,最终可能用于修复心脏病发作和中风后受损的心脏和血管。在这里,我们将使用小鼠干细胞来发现负责细胞可塑性和记忆的遗传因素,以便创造出可用于修复环境的心脏和血管细胞的纯群体。
英文摘要
Several recent breakthroughs have made us realise that there is a lot of plasticity in cellular development, and we can now harness this plasticity to create stem cells that may eventually be used to repair the damaged heart and blood vessels after heart attacks and stroke. Here we will use mouse stem cells to discover the genetic factors responsible for a cell’s plasticity and memory in order to create pure populations of heart and blood vessel cells that can be used in repair settings.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Roles of the EMT transcription factors in epigenetic remodelling and myeloid cell transformation.
-
批准号:nhmrc : GNT1141081
-
项目类别:Project Grants
-
资助金额:$80.95万
-
财政年份:2018
-
负责人:A/Pr Jody Haigh
-
依托单位:
Roles of the EMT transcription factors in epigenetic remodelling and myeloid cell transformation.
-
批准号:nhmrc : 1141081
-
项目类别:Project Grants
-
资助金额:$54.73万
-
财政年份:2018
-
负责人:A/Pr Jody Haigh
-
依托单位:
Role of ZEB/NuRD interactions in Haematopoiesis and Lymphoid Malignancies
-
批准号:nhmrc : GNT1104441
-
项目类别:Project Grants
-
资助金额:$81.05万
-
财政年份:2016
-
负责人:A/Pr Jody Haigh
-
依托单位:
Role of ZEB/NuRD interactions in Haematopoiesis and Lymphoid Malignancies
-
批准号:nhmrc : 1104441
-
项目类别:Project Grants
-
资助金额:$55.59万
-
财政年份:2016
-
负责人:A/Pr Jody Haigh
-
依托单位:
Role of Zeb2/Sip1 in Leukaemic Stem Cell Formation and Cancer Progression
-
批准号:nhmrc : 1047995
-
项目类别:Project Grants
-
资助金额:$43.69万
-
财政年份:2013
-
负责人:A/Pr Jody Haigh
-
依托单位:
海外基金