Identification and chracterization of host cell receptors for influenza A viruses

吸入后，流感病毒感染免疫系统细胞和呼吸道上皮细胞。目前还不清楚流感病毒是如何附着并感染这些细胞的。本项目将采用新的方法鉴定人类上皮细胞和免疫细胞上的流感病毒受体。这些受体的最终鉴定将对开发治疗流感病毒感染的新药具有重要意义。

Following inhalation, influenza virus infects cells of the immune system and epithelial cells lining the airways. Currently, it is not clear how influenza virus attaches to and infects these cells. This project will use new ways to identify receptors for influenza virus on human epithelial cells and immune cells. The ultimate identification of these receptors would have important implications for the development of new drugs to treat influenza virus infections.