SYNTHESIS OF MARINE DERIVED MACROCYCLIC SALICYLATES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们实验室的研究重点是复杂分子结构的合成;特别是具有新颖结构特征和有趣生物功能的天然物质。在特定天然产物目标的组装过程中经常遇到的不可预测和独特的化学反应模式继续挑战合成化学家。利用UT西南的研究环境，我们越来越多地将分子药理学和生物化学方面整合到我们的研究计划中。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Research in our laboratory focuses on the synthesis of complex molecular architectures; in particular naturally occurring substances with novel structural features and interesting biological function. Unpredictable and unique chemical reactivity patterns oftentimes encountered during the assembly of a particular natural product target continues to challenge synthetic chemists. Taking advantage of the research environment at UT Southwestern, we are increasingly integrating molecular pharmacology and biochemical aspects into our research program.