DYNAMIC PULMONARY IMAGING USING DYNAMIC CONTRAST-ENHANCED MR IMAGING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者的研究机构。 使用超极化气体、氦气和氙气进行螺旋成像，在啮齿动物肺部进行真正的动态成像。 第一个目标是了解呼吸周期的动力学，并仅执行质子扫描以优化螺旋序列的成像和定时参数。下一个目标是扩展这些扫描，以证明执行动态高压气体研究的能力。 这些研究将影响该中心今后的工作。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Perform true dynamic imaging in rodent lungs using spiral imaging using hyperpolarized gases, Helium and Xenon. The first goal is to understand the dynamics of the respiratory cycle, and perform only proton scans to optimize the imaging and timing parameters of the spiral sequence. The next goal is to extend these scans to demonstrate the capability of performing dynamic HP gas studies. These studies will impact future work in the Center.