Identification of neuroprotective therapies for the treatment of demyelinating disease
Identification of neuroprotective therapies for the treatment of demyelinating disease
批准号:
nhmrc : 509088
负责人:
Prof Gary Egan
金额:
$12.82万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2008-12-31
来源:
中文摘要
多发性硬化症(MS)的脑保护在MS中,免疫系统反复攻击大脑。不幸的是,一些由此产生的损害无法修复,因为它破坏了一些电缆(轴突)。在人类中,轴突的破坏是永久性的,并且由于反复发作而导致的累积轴突损失最终导致进行性残疾,包括截瘫、痴呆、失明和失禁。该提案旨在确定减少MS轴突损伤的治疗方法。
英文摘要
Brain protection for Multiple Sclerosis (MS) In MS, the immune system repeatedly attacks the brain. Unfortunately, some of the resultant damage cannot be repaired, because it destroys some of the electrical cables (axons). In humans, destruction of axons is permanent and cumulative axonal loss due to repeated attacks ultimately leads to progressive disablity including, paraplegia, dementia, blindness and incontinence. This proposal aims to identify treatments to reduce axonal damage in MS.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Near Infrared Fluorescence and Photoacoustic Imaging Facility
-
批准号:LE220100140
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$46.66万
-
财政年份:2022
-
负责人:Prof Gary Egan
-
依托单位:
A national Magnetic Particle Imaging facility
-
批准号:LE190100084
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$59.91万
-
财政年份:2019
-
负责人:Prof Gary Egan
-
依托单位:
Integrative brain imaging technologies
-
批准号:LP170100494
-
项目类别:Linkage Projects
-
资助金额:$47.57万
-
财政年份:2019
-
负责人:Prof Gary Egan
-
依托单位:
ARC Centre of Excellence for Integrative Brain Function
-
批准号:CE140100007
-
项目类别:ARC Centres of Excellence
-
资助金额:$1445.24万
-
财政年份:2014
-
负责人:Prof Gary Egan
-
依托单位:
An integrative and distributed data management and workflow framework for e-research in biomedical imaging
-
批准号:LP110100470
-
项目类别:Linkage Projects
-
资助金额:$25.28万
-
财政年份:2011
-
负责人:Prof Gary Egan
-
依托单位:
Development of ultrahigh resolution brain imaging for investigating neurological and neurodegenerative diseases
-
批准号:nhmrc : 1003993
-
项目类别:Research Fellowships
-
资助金额:$58.71万
-
财政年份:2011
-
负责人:Prof Gary Egan
-
依托单位:
Investigating evidence of control system dynamics in visuomotor skill acquisition using multimodal functional magnetic resonance imaging.
-
批准号:DP0985143
-
项目类别:Discovery Projects
-
资助金额:$17.68万
-
财政年份:2009
-
负责人:Prof Gary Egan
-
依托单位:
eResearch in the Neurosciences: Building collaborations in Asia
-
批准号:LX0882711
-
项目类别:Linkage - International
-
资助金额:$1.63万
-
财政年份:2008
-
负责人:Prof Gary Egan
-
依托单位:
Research Fellowship - Grant ID:400317
-
批准号:nhmrc : 400317
-
项目类别:NHMRC Research Fellowships
-
资助金额:$36.6万
-
财政年份:2006
-
负责人:Prof Gary Egan
-
依托单位:
Data Management Technologies for the Magnetic Resonance Imaging e-Research Grid
-
批准号:LP0667490
-
项目类别:Linkage Projects
-
资助金额:$45.37万
-
财政年份:2006
-
负责人:Prof Gary Egan
-
依托单位:
MRI GRID Computing Facility: Design, Optimisation and Image Processing
-
批准号:LE0561231
-
项目类别:Linkage Infrastructure, Equipment and Facilities
-
资助金额:$44.79万
-
财政年份:2005
-
负责人:Prof Gary Egan
-
依托单位:
Development of e-Research Tools for an MRI Grid Computing Facility
-
批准号:SR0564829
-
项目类别:Special Research Initiatives
-
资助金额:$5.5万
-
财政年份:2005
-
负责人:Prof Gary Egan
-
依托单位:
Uncoupled Research Fellowship
-
批准号:nhmrc : 217019
-
项目类别:NHMRC Research Fellowships
-
资助金额:$26.61万
-
财政年份:2002
-
负责人:Prof Gary Egan
-
依托单位:
国内基金
海外基金
骨髓抑制再生单个核细胞移植通过调节线粒体功能在脑缺血再灌注损伤中的神经保护机制研究
-
批准号:82371301
-
项目类别:面上项目
-
资助金额:49.00万元
-
批准年份:2023
-
负责人:李轶
-
依托单位:
新型四环素类似物的优化设计、合成及神经保护作用研究
-
批准号:20972011
-
项目类别:面上项目
-
资助金额:35.0万元
-
批准年份:2009
-
负责人:刘俊义
-
依托单位:
新型神经元保护剂的设计合成和活性评估
-
批准号:20372005
-
项目类别:面上项目
-
资助金额:23.0万元
-
批准年份:2003
-
负责人:刘俊义
-
依托单位: