Tools for Economic Analysis of Patient Management Interventions in Heart Failure

描述(由申请人提供)：为了使社会医疗保健资金的价值最大化，各级决策者需要工具来系统地比较与医疗保健干预相关的成本和收益。评估以患者为中心的干预措施的成本效益尤其具有挑战性，特别是在对此类干预措施进行准确和全面的成本评估并预测其对健康和生活质量的长期影响方面。拟议的项目Team-HF：心力衰竭患者管理干预措施的经济分析工具旨在开发工具，促进对心力衰竭的健康护理干预措施进行高质量的经济评估，特别是那些涉及以患者为中心的教育或行为矫正因素的干预措施。本申请概述了4个项目，这些项目将(1)帮助应用标准成本计算方法；(2)促进进行正式的成本效益分析；(3)展示疾病模拟建模在寻找更高计划效率和高价值研究机会方面的力量。在第一个项目中，将设计一个由一系列电子表格组成的成本计算工具，以系统地估计与实施和维持以患者为中心的干预措施相关的成本。该工具可以应用于针对任何医疗条件的程序。第二个项目涉及开发一种用户友好的、概率的疾病模拟模型，以评估心力衰竭的短期和长期成本和健康结果。这一工具可以应用于以患者为中心或为心力衰竭患者提供的其他医疗干预。该模型将利用最近完成的一项由美国国立卫生研究院赞助的大型心力衰竭试验(HF-ACTION)的丰富纵向数据集来开发。成本计算工具和疾病模拟模型都将使用Microsoft Excel开发，以便向潜在用户广泛传播。第三和第四个项目将使用疾病模拟模型来反向设计以患者为中心的干预措施，这些干预措施最有可能具有成本效益，并进行信息价值分析，以确定未来研究工作的优先顺序。 与公共卫生相关：越来越有必要限制美国卫生支出的增长。经济评估为区分价值较高和价值较低的保健干预措施提供了一种工具。Team-HF项目将为临床医生和研究人员提供用户友好的工具，以促进对以患者为中心的干预措施进行高质量的经济评估。

DESCRIPTION (provided by applicant): To maximize the value of society's health care dollars, decision makers at all levels need tools to systematically compare costs and benefits associated with health care interventions. Evaluating the cost-effectiveness of patient-focused interventions is particularly challenging, especially in developing accurate and comprehensive cost assessments of such interventions and projecting their long-term impact on health and quality of life. The objective of the proposed project, TEAM-HF: Tools for Economic Analysis of Patient Management Interventions in Heart Failure, is to develop tools to facilitate the conduct of high-quality economic evaluations of health care interventions in heart failure, particularly those that involve patient-focused educational or behavioral modification elements. This application outlines 4 projects that will (1) aid in the application of standard costing methods; (2) facilitate the conduct of formal cost-effectiveness analyses; and (3) demonstrate the power of disease simulation modeling in identifying opportunities for greater program efficiency and high-value research. In the first project, a costing tool composed of a series of spreadsheets will be designed to systematically estimate costs associated with implementing and maintaining a patient-focused intervention. This tool could be applied to programs targeting any medical condition. The second project involves the development of a user-friendly, probabilistic, disease simulation model to evaluate short- and long-term costs and health outcomes in heart failure. This tool could be applied to patient-focused or other medical interventions provided to patients with heart failure. The model will be developed using a rich set of longitudinal data from a recently completed, large NIH-sponsored trial in heart failure (HF-ACTION). Both the costing tool and the disease simulation model will be developed using Microsoft Excel to allow for wide dissemination to potential users. The third and fourth projects will use the disease simulation model to reverse engineer patient-centered interventions that are most likely to be cost-effective and to conduct value-of-information analyses to prioritize future research efforts. PUBLIC HEALTH RELEVANCE: There is an increasing need to limit growth in health spending in the United States. Economic evaluation provides a tool to discriminate between higher-value and lower-value health care interventions. The TEAM-HF projects will provide clinicians and researchers with user-friendly tools to facilitate the conduct of high-quality economic evaluations of patient-focused interventions.