PILOT PROJECT AND EMERGING OPPORTUNITIES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 这个项目和伴随的资源最初分配给马修波因特博士谁已经“毕业”。 目前，我们只剩下一年的资金。 当前的金融危机并没有幸免于学术也没有系，学院和佛蒙特大学。 该机构已冻结招聘，但高级招聘（副总裁，院长等）除外。裁员也在计划中 然而，国会的经济刺激方案也创造了无与伦比的融资机会。 鉴于这种不寻常的情况，我们认为，目前最谨慎的做法是将该项目的资源用于两个相互关联的目的。 我们将资助小型试点项目，其目标是快速提交R21或类似赠款。 我们目前正在进行一项计划项目的工作，这些资源将被用来促进这项工作，特别是初步数据的问题。 几名COBRE受训人员（例如狄克逊、苏拉特）也在编写第二份R 01应用程序，因此需要额外的支持来获取关键的初步数据。 审查和申请过程将是快速的，但竞争激烈。 申请人将在我们每周的资助智囊团会议上提出他们的想法，具体目标和项目大纲，然后准备一张纸（2-5页）申请。 申请将由IAC审查，并酌情作出资助决定。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project and attendant resources was originally assigned to Dr. Matthew Poynter who has since "graduated". At this juncture we only have a single year remaining of funding. The current financial crisis has not spared the academic nor the Department, College and University of Vermont. This institution has instituted hiring freezes except for high level recruitments (vice presidents, deans, etc.) and layoffs are planned. However, the congressional economic stimulus package has also created unparalleled funding opportunities. In light of this unusual situation we believe that the most prudent thing to do at this point is to use the resources of this project for two interrelated purposes. We will fund small pilot projects that have as their goal the rapid submission of R21 or similar grants. We are currently in the throws of a Program Project effort and these resources will be utilized to catalyze this effort, specifically a question of preliminary data. Several COBRE trainees (e.g. Dixon, Suratt) are also writing a second R01 application and accordingly will need extra support to acquire critical preliminary data. The review and application process will be rapid but competitive. Applicants will present their ideas, specific aims and project outlines in our weekly grant think tank meetings and then prepare a sheet (2-5 pages) application. Applications will be reviewed by the IAC and funding decisions made as appropriate.