Training in Endocrine, Metabolic, and Prenatal Basis of Chronic Kidney Disease

描述(由申请人提供)： 这是一个关于慢性肾脏疾病的内分泌、代谢和围产期基础的培训计划的修订申请，以支持3名博士前实习生。总体目标是培养出具有强大翻译能力的高质量独立调查人员，他们能够开发和维持优秀的研究项目。培训教师由来自医学院、药学和兽医学院6个系的23名导师组成。该学院由基础科学家和临床医生科学家组成，他们具有广泛的兴趣和专业知识，其中大部分专注于内分泌-心脏肾相互作用。这些博士前实习生将通过医学院的生物医学跨学科项目(IDP)进行招募和培训。在过去3年中，来自全美的符合培训资助资格的候选人平均为170人/年，其中约50人/年进入培训计划。这些学员的平均口语和定量综合GRE成绩为1200-1250分，本科GPA为3.5分。IDP提供全面的讲座和实验室课程，以及实验室轮换和专门学科的高级课程工作。随后的培训侧重于在选定的实验室进行独立研究，以及发展交流技能和研究伦理方面的补充培训。该培训计划的核心课程旨在为学生提供适合从事慢性肾脏疾病内分泌、代谢和产前基础工作的研究人员的知识。博士前培训通常需要大约5年，第一年由各自的学院提供，平均3-4年的支持来自培训补助金和由导师研究补助金提供的额外资金。

DESCRIPTION (provided by applicant): This is a revised application for a training program in Endocrine, Metabolic, and Perinatal Basis of Chronic Kidney Disease to support 3 predoctoral trainees. The overall goal is to produce top quality independent investigators with a strong translational approach who can develop and sustain outstanding research programs. The training faculty consists of 23 mentors from 6 departments in the Colleges of Medicine, Pharmacy, and Veterinary Medicine. The faculty consists of basic scientists and clinician-scientists with a wide range of interests and expertise, much of which is focused on endocrine-cardiorenal interactions. The predoctoral trainees will be recruited and trained through the College of Medicine's Interdisciplinary Program in Biomedical Sciences (IDP). The pool of trainee grant eligible candidates from the entire US has averaged 170/year during the past 3 years with ~ 50/year entering the training program. These trainees enter with an average combined verbal plus quantitative GRE scores of ~1200-1250, and undergraduate GPAs of ~3.5. The IDP provides comprehensive lecture and laboratory courses as well as laboratory rotations and advanced course work in specialized disciplines. Subsequent training focuses on independent research in the laboratory of choice as well as supplemental training in development of communication skills and ethical aspects of research. A core curriculum for this training program has been designed with the intent of providing the students with the knowledge appropriate for researchers working on the endocrine, metabolic, and prenatal basis of chronic kidney disease. The predoctoral training usually takes ~ 5 years with the first year provided by the respective college, an average of 3-4 years support anticipated from the training grant and additional funds supplied by the mentors research grants.