Training in Muscle Biology and Muscle Disease

描述（由申请人提供）：宾夕法尼亚大学的肌肉和运动社区建议建立一个肌肉生物学和肌肉疾病的培训计划，部分由T32机制支持。宾夕法尼亚大学社区的成员在肌肉研究方面享誉全球，但目前还没有统一的肌肉训练计划。宾夕法尼亚大学没有T32相关的肌肉生物学赠款。因此，我们开发了一个新的培训计划，其中包括与肌肉生物学和疾病培训直接相关的新研究生课程。我们提出的培训计划将支持2名博士前学生和2名博士后学生，使他们能够在主要研究人员指导的20个实验室中的任何一个工作，这些主要研究人员是细胞生物学，遗传学，生理学和/或肌肉病理学研究的领导者。虽然培训师的兴趣和专业知识范围很广，但培训的重点是阐明肌肉功能和疾病的机制。该计划旨在利用教师的高度协作性，从而为学员提供将肌肉生物学的分子和临床方面整合到他们的研究中的机会。这种多样性为肌肉生物学领域提供了无与伦比的训练环境。世界各地许多杰出的科学家都在宾夕法尼亚大学接受过这一领域的培训，这证明了这一点。

DESCRIPTION (provided by applicant): The muscle and motility community at the University of Pennsylvania proposes to establish a training program in Muscle Biology and Muscle Disease, to be supported in part by the T32 mechanism. Members of the Penn community are known world-wide for excellence in muscle research, yet a unified muscle training program does not currently exist. There are no T32-related muscle biology grants at the University of Pennsylvania. Therefore, we developed a, new training program that includes new graduate-level courses that relate directly to training in muscle biology and disease. Our proposed training program would support 2 predoctoral students and 2 postdoctoral students, enabling them to work in any of 20 laboratories directed by principal investigators who are leaders in the study of the cell biology, genetics, physiology, and/or pathology of muscle. Although the range of interests and expertise of the trainers on this grant is broad, the training is focused on elucidating the mechanisms of muscle function and disease. The program is designed to take advantage of the highly collaborative nature of the faculty, thus providing the trainees with the opportunity to integrate molecular and clinical aspects of muscle biology into their research. This diversity provides for the potential for an unparalleled training environment in the area of muscle biology. This is evidenced by the many prominent scientists around the world who have trained in this field at the University of Pennsylvania.