Renal Control of Body Composition and Blood Pressure

描述(由申请人提供)： 这是德克萨斯大学西南医学中心肾脏病研究博士后培训计划的修订申请。拟议的应用程序将把两个现有的培训计划合并为一个计划，一个是成人肾病(T32 DK07257-25)，另一个是儿童肾病(T32 DK07659-15)。合并的理由包括项目主任的相似研究兴趣、高度整合的培训项目(包括共享的受训者)、重叠的课程以及几乎相同的培训教师。该计划的主要目的仍然是培训内科科学家，他们将研究肾脏生物学和疾病，并将这些知识转化为改善患者护理的知识。在过去的25年里，该培训计划一直得到持续资助。申请者群体继续保持强劲，许多毕业生为生物医学研究做出了重要贡献，并获得了外部资金用于他们的研究。该计划的教职员工包括25名内科科学家和基础科学家，他们拥有与肾脏相关的广泛科学学科的专业知识。培训计划分为四个基础科学研究项目(肾脏生理学和细胞生物学、肾脏损伤和修复的病理生理学、肾脏发育和多囊肾病)和四个面向患者的研究项目(慢性肾脏疾病、高血压和心血管疾病、电解质和矿物质代谢以及人类遗传学)。每个项目都包括临床和基础科学教员以及正式的教学课程。课程包括伦理和负责任的研究行为的必修课，职业发展的专题，一个期刊俱乐部以及西南研究生院基础科学分部的精选选修课。以患者为中心的研究课程包括以患者为中心的研究技术研讨会、以患者为中心的研究培训计划(K30奖项)、临床科学硕士学位。

DESCRIPTION (provided by applicant): This is a revised application for continuation of the postdoctoral training program in nephrology research at the University of Texas Southwestern Medical Center. The proposed application will combine the two existing training programs, one in adult nephrology (T32 DK07257-25) and one in pediatric nephrology (T32 DK07659-15), into a single program. The rationale for this merger includes the similar research interests of the program directors, the highly integrated training programs including shared trainees, the overlapping curricula, and the nearly identical training faculty. The primary purpose of the program remains the training of physician-scientists who will investigate kidney biology and disease and translate this knowledge into improvements in patient care. The training program has been continuously funded for the past 25 years. The applicant pool continues to be strong, and many of the graduates have made important contributions to biomedical research and have received external funding for their research. The program faculty comprises 25 physician-scientists and basic scientists with expertise in a broad range of scientific disciplines that are relevant to the kidney. The training program is organized into four programs in basic science research (Renal Physiology & Cell Biology, Pathophysiology of Renal Injury & Repair, Kidney Development, and Polycystic Kidney Disease) and four programs in patient-oriented research (Chronic Kidney Disease, Hypertension & Cardiovascular Disease, Electrolyte & Mineral Metabolism, and Human Genetics). Each program includes clinical and basic science faculty and a formal didactic curriculum. The curriculum consists of required courses in ethics and the responsible conduct of research, special topics in career advancement, and a journal club as well as selected elective courses from the Southwestern Graduate School Division of Basic Science. The curriculum for patient-oriented research consists of a Symposium on Techniques of Patient- Oriented Research, a training program in patient-oriented research (K30 award), a Masters Degree in Clinical Science.