Training in HIV Replication and Pathogenesis

描述（由申请人提供）：拟议的博士前培训计划的总体目标是贡献高度创造性，生产力和训练有素的艾滋病毒/艾滋病研究人员，以满足国家卫生和研究的优先事项。这一目标将通过在医学和牙科（URMSD）的罗切斯特学校的完善的跨部门研究生培训环境中培养一批博士前学生来实现，在经验丰富和充满爱心的导师的监督下。这一高度互动的核心环境将由以下方面促进：一个致力于卓越教学和研究并致力于艾滋病毒/艾滋病研究培训的教师;该方案教师的杰出艾滋病毒/艾滋病研究方案;在艾滋病毒/艾滋病研究的各个方面的讲座课程和结构化研讨会;期刊俱乐部;精心设计的丰富活动和讲习班;以及催化数量的受训人员。在艾滋病毒/艾滋病研究范围内的各种有关问题的研究机会将提供给学员由经验丰富的导师与强大的校外资金和建立合作的历史。该方案的具体目标如下：1.发展一个互动的，富有成效的和令人兴奋的跨学科的环境，其中博士前学员获得在艾滋病毒/艾滋病研究领域的杰出教育。这将通过整合来自几个不同部门和学科的教师来实现。2.为学生提供丰富的培训和学习环境，技能研讨会，结构化的研讨会计划和期刊俱乐部，杰出的校外演讲者，职业发展活动，加强负责任的研究行为培训，以及指导培训的机会。学生还将接受培训，以评估和撰写手稿和赠款申请。3.通过上述项目促进学员和教师之间的沟通。这将利用URSMD提供的亲密环境，所有参与的教师和学员都在同一个物理空间内，在一个屋檐下一起工作。4.支持三个主要重点领域的培训工作：（i）病毒复制和逆转录，（ii）病毒免疫学和疫苗生物学，（iii）病毒发病机理，特别强调神经艾滋病和控制病毒复制的宿主因素。

DESCRIPTION (provided by applicant): The overall goal of the proposed predoctoral training program is to contribute highly creative, productive and well trained HIV/AIDS researchers to meet national health and research priorities. This goal will be achieved by having a cadre of predoctoral students train in the well-established interdepartmental graduate training milieu of the University of Rochester School of Medicine and Dentistry (URMSD), under the supervision of experienced and caring mentors. This highly interactive core environment will be fostered by: a faculty dedicated to excellence in teaching and research and committed to training in HIV/AIDS research; outstanding HIV/AIDS research programs of the program faculty; lecture courses and structured seminars in various aspects of HIV/AIDS research; journal clubs; well-designed enrichment activities and workshops; and a catalytic number of trainees. Research opportunities in a wide variety of relevant problems within the purview of HIV/AIDS research will be offered to trainees by experienced mentors with strong extramural funding and an established history of collaboration. Specific objectives of the program are as follows: 1. To develop an interactive, productive and exciting interdisciplinary environment in which predoctoral trainees obtain an outstanding education in the area of HIV/AIDS research. This will be achieved by integrating faculty from several different departments and disciplines. 2. To provide an enriched training and learning environment for students, with skills workshops, structured seminar programs and journal clubs, distinguished extramural speakers, career development activities, enhanced training in the responsible conduct of research, and opportunities for training in mentoring. Students will also be trained to evaluate and write both manuscripts and grant applications. 3. To foster communication among trainees and faculty through the programs outlined above. This will exploit the intimate environment provided at the URSMD, where all the participating faculty and trainees work together in the same physical space, under a single roof. 4. To support training efforts in three major emphasis areas: (i) viral replication and reverse transcription, (ii) viral immunology and vaccine biology, and (iii) viral pathogenesis, with special emphasis on neuroAIDS and host factors that control virus replication.