Cancer Epidemiology

癌症流行病学研究项目使用流行病学数据来增强我们对 癌症发病率和治疗，并探索如何利用这些信息来降低癌症发病率 并改善结果。该计划成员的总体目标是进行流行病学研究 这将为教育和面向服务的活动提供更多的知识，旨在减少 癌症发病率，提高存活率，改善生活质量。有五个主要的重叠焦点 在项目研究的保护伞范围内的领域。 主题1-癌症病因学 主题2--癌症保健服务和成果 主题3-头颈癌的流行病学 主题4-癌症预防和控制 主题5--癌症与老龄化。 癌症流行病学计划在过去资助期间取得的主要成就实例 包括：(A)描述农业健康研究中关于农药和癌症的新发现 队列，(B)报告住宅氡和肺癌的剂量-反应优势比更高，可能是由于 更准确的暴露评估，(C)妇女健康倡议关于激素治疗的调查结果 最后建议不要采取激素疗法来预防心脏病，以及(D) 发现卵巢癌的应激机制与血管生成细胞因子有关。有很多种 过去和现在在本计划成员之间以及与 其他癌症中心项目。目前的例子包括肺癌护理结果/监测 联合体研究，淋巴瘤孢子，癌症与衰老P20，健康有效性研究 人类乳头瘤病毒和癌症研究中心，爱荷华州综合癌症控制联盟， 和爱荷华州癌症登记处。该计划由来自13个系和5所学院的26名成员组成。 目前，经过同行评审的癌症相关研究，该项目的年度直接资金总额为6,020,366美元，其中 来自NCI的2,334,604美元。

Research in the Cancer Epidemiology Program uses epidemiologic data to enhance our understanding of cancer incidence and therapy, and to explore how we can use this information to decrease cancer incidence and improve outcome. The overall goal of the members of this program is to perform epidemiologic research that will provide additional knowledge for educational and service-oriented activities aimed at decreasing cancer incidence, increasing survival, and improving quality of life. There are five major overlapping focus areas within the umbrella of the Program's research. Theme 1 - Cancer etiology Theme 2 - Cancer health services and outcomes Theme 3 - The epidemiology of head and neck cancer Theme 4 - Cancer prevention and control Theme 5 - Cancer and aging. Examples of major accomplishments of the Cancer Epidemiology Program over the past funding period include (a) description of novel findings regarding pesticides and cancer from the Agricultural Health Study cohort, (b) reporting of stronger dose-response odds ratios for residential radon and lung cancer likely due to more accurate exposure assessment, (c) the Women's Health Initiative findings on hormone therapy that concluded with a recommendation that hormone therapy not be taken to prevent heart disease, and (d) the discovery that stress mechanisms are related to angiogenic cytokines in ovarian cancer. There are numerous past and present productive collaborations both between members of the Program, and with members of other Cancer Center Programs. Current examples include the lung cancer care outcomes/surveillance consortium study, the Lymphoma SPORE, the Cancer and Aging P20, the Health Effectiveness Research Center, studies of human papillomavirus and cancer, the Iowa Comprehensive Cancer Control Consortium, and the Iowa Cancer Registry. The program consists of 26 members from 13 departments and 5 colleges. Current, peer-reviewed, cancer-related research, annual direct funding for this program totals $6,020,366 with $2,334,604 coming from the NCI.