Faculty Recruitment in Novel Therapeutic Strategies for Neurodegenerative Disease

描述(由申请者提供)：本提案寻求通过生物医学研究核心中心(P30)机制支持埃默里大学在神经退行性疾病的新治疗策略领域招聘新的教员以增强机会研究能力。作为中心主任，Raymond Dingledine博士(医学院药理学主席、教授和执行副院长)将与Allan Levey博士(神经病学主席兼教授和神经退行性疾病中心主任)和Lian Li(副主任兼药理学教授)一起招聘和指导一位积极进取的终身教职助理教授，进行专注于神经退行性疾病的基础和/或翻译研究，与开发抗击神经退行性疾病的新治疗策略相关的研究。新招聘的调查员将在药理学系获得初级任命，并在神经内科和神经退行性疾病中心获得二级任命。核心中心将利用在空间、人员和其他资源方面的慷慨机构支持，提供卓越、协作和跨学科的环境，以及全面、彻底和严格的教师发展和评估计划，以促进新教师的独立研究生涯和专业发展。实现本申请中提出的目标将扩大和扩大Emory专注于神经退行性疾病的基础、翻译和临床研究的多学科研究人员社区，建立和加强不同部门之间的内部关系，包括药理学和神经病学系、神经退行性疾病中心、综合神经科学研究所、化学生物学发现中心和药物发现研究所，并促进治疗神经退行性疾病的新治疗方法的开发。 与公共卫生相关：随着人口老龄化，神经退行性疾病正变得越来越常见，但目前还没有治愈方法来阻止这些毁灭性疾病的发展。本申请中描述的计划将增强Emory在神经退行性疾病研究方面的多学科研究能力，并促进抗击神经退行性疾病的新治疗策略的开发。

DESCRIPTION (provided by applicant): This proposal seeks support for new faculty recruitment to chance research capacity at Emory University in the area of novel therapeutic strategies for neurodegenerative disease through the biomedical research core center (p30) mechanism. As the center director, Dr. Raymond Dingledine (Chairman and Professor of Pharmacology and the Executive Associate Dean for Research in the School of Medicine) will work with Drs. Allan Levey (Chairman and Professor of Neurology and Director of Center for Neurodegenerative Disease) and Lian Li (Vice Chair and Professor of Pharmacology) to recruit and mentor a highly motivated tenure- track Assistant Professor to conduct research focusing on the basic and/or translational studies of neurodegenerative disease, with relevance to the development of novel therapeutic strategies for combating neurodegeneration. The newly-recruited investigator will have primary appointment in the Department of Pharmacology and secondary appointments in the Department of Neurology and the Center for Neurodegenerative Disease. The core center will leverage generous institutional support for space, personnel, and other resources and provide an outstanding, collaborative, and interdisciplinary environment and a comprehensive, thorough, and rigorous faculty development and evaluation plan that foster independent research career and professional development of the new faculty member. Achieving the goals proposed in this application will augment and expand Emory's community of multidisciplinary researchers focusing on the basic, translational, and clinic studies of neurodegenerative diseases, establish and strengthen the intra-institutional relationships among various components, including Departments of Pharmacology and Neurology, Center for Neurodegenerative Disease, Comprehensive Neuroscience Institute, Chemical Biology Discovery Center, and Drug Discovery Institute, and facilitate the development of novel therapeutic approaches for treating neurodegenerative diseases. PUBLIC HEALTH RELEVANCE: Neurodegenerative diseases are becoming more common as the population ages, but currently there is no cure to stop the progression of these devastating illnesses. The plans described in this application will enhance Emory's multidisciplinary research capacity on the studies of neurodegenerative diseases and promote the development of new therapeutic strategies for combating neurodegeneration.