A PROSPECTIVE COHORT STUDY OF CHRONIC RENAL INSUFFICIENCY

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本研究是对NIH NIDDK RFA的回应，旨在对肾功能不全（也称为慢性肾脏疾病（CKD））患者进行多中心观察性研究。 主要目的是确定CKD快速进展的风险因素，并确定该人群中动脉粥样硬化性心血管疾病的发病率和风险因素。 CRIC研究将招募3000名不同严重程度肾脏疾病的个体，以确保有足够数量的患者达到主要研究终点。 队列成员将接受长达5年的随访。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study is in response to an RFA from the NIH NIDDK to conduct a multi-center observational study of patients with renal insufficiency, otherwise referred to as chronic kidney disease (CKD). The primary aim is to determine risk factors for rapid progression of CKD, and determine the incidence of and risk factors for atherosclerotic cardiovascular disease in this population. The CRIC study will enroll 3000 individuals across the spectrum of severity of renal disease to assure that a sufficient number of patients reach the primary study endpoints. Cohort members will be followed for up to 5 years.