INBRE: COLLEGE OF CHARLESTON: FACULTY & UNDERGRADUATE RESEARCH DEVELOPMENT

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 查尔斯顿学院提案的主题是“疾病过程的分子模型和化学方法”。该分项目的重点是支持生物学和化学/生物化学两个系的五名“目标教师”，以及每年在目标学院的指导下积极参与研究的大量本科生。这些学生中有几个已经毕业并继续读研究生。其中三名研究人员除了使用老鼠外，还使用果蝇作为模型生物。该项目的总体目标是：1)使目标学院成为独立的调查人员，2)增加学生，特别是少数族裔学生对有意义的研究经历的参与，包括出版和介绍他们的工作。除了INBRE奖之外，学院还为以下方面提供重要的财政支持：a)目标教师的研究发布时间，b)关键仪器，以及c)目标教师和学生的用品和旅费。预计每个目标教员都要制定一份职业计划，定期与他/她的导师讨论，所有的职业计划都包括提交NIH拨款提案作为一个关键的里程碑。预计到授权期结束时，学院在生物医学研究方面的竞争力将显著高于该奖项开始时的水平。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The theme of the College of Charleston proposal is "Molecular Models and Chemical Approaches to Disease Processes." The subproject focuses on support for five "target faculty" from two departments, Biology and Chemistry/Biochemistry, and for a large number of undergraduate students each year who actively participate in research under the guidance of the Target Faculty. Several of these students have graduated and have gone on to graduate school. Three of the investigators are using Drosophila menalogaster as a model organism in addition to using the mouse. The overall aims of the project are: 1) to enable the Target Faculty to become independent investigators, and 2) to increase the participation of students, especially minority students, in meaningful research experiences, including publication and presentation of their work. The College is providing significant financial support over and above the INBRE award for: a) research release time for Target Faculty, b) key instrumentation, and c) supplies and travel for Target Faculty and students. Each Target Faculty member is expected to develop a career plan that is regularly discussed with his/her mentor and all career plans include the submission of an NIH grant proposal as a key milestone. It is anticipated that by the end of the grant period, the College will be significantly more competitive in biomedical research than it was at the initiation of this award.