Chile Fetal Alcohol Study
Chile Fetal Alcohol Study
批准号:
7968711
负责人:
James Mills
金额:
$31.56万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
11-dehydro-thromboxane B2Adverse effectsAgeAlcohol abuseAlcohol-Related Neurological DefectsAlcoholsCategoriesChildChileClassificationDataData SetDefectEicosanoidsExposure toEyeEye AbnormalitiesFetal Alcohol Spectrum DisorderFetal Alcohol SyndromeFetusHeavy DrinkingHome visitationHormonesHouse CallInjuryLifeLinkMeasuresMothersNational Institute of Child Health and Human DevelopmentNeural ConductionOnly ChildOphthalmic examination and evaluationOutcomeOxidative StressPathogenesisPatternPopulationPregnancyProspective StudiesProstaglandinsRecording of previous eventsRefractoryReportingResearch DesignRiskRoleScreening procedureUniversitiesVasoconstrictor AgentsVasodilator AgentsVisual AcuityWomanalcohol exposurealcohol measurementbasedrinkingexperiencefetalhigh riskin uterointerestisoprostaglandin F2alpha type-IIImalformationoffspringpregnantprenatalprostaglandin F1urinaryvasoconstriction
中文摘要
迄今为止,这项研究表明,在子宫内接触大量酒精的儿童,尽管没有典型的胎儿酒精综合征,但神经传导速度异常。该研究还表明,眼部异常的风险仅限于那些患有胎儿酒精综合征的人;其他重度暴露的儿童则没有过多的眼部缺陷。这项研究已经完成了对所有受辐射对象的分类,并根据他们所经历的不良影响进行了分类。现在可以根据经典胎儿酒精综合征(FAS)或胎儿酒精谱系障碍或酒精相关神经缺陷的类别对受试者进行分析。这将有可能将暴露儿童的结果与产前收集的酒精暴露数据联系起来。
英文摘要
To date this study has shown that children exposed to large quantities of alcohol in utero have abnormal nerve conduction velocities despite not having classic fetal alcohol syndrome. The study has also shown that the risk of ophthalmologic abnormalities is limited to those who have fetal alcohol syndrome; other heavily exposed children did not have a excess of eye defects. The study has completed the classification of all exposed subjects into categories that define the adverse effects that they have experienced. Subjects can now be analyzed based on the categories of classic fetal alcohol syndrome (FAS) or fetal alcohol spectrum disorder or alcohol related neurological defects. This will make it possible to link outcomes in exposed children to data on alcohol exposure collected during their prenatal life.
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Genetic Factors in Birth Defects
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批准号:9150120
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项目类别:
-
资助金额:$33.61万
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财政年份:--
-
负责人:James Mills
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依托单位:
NICHD Health Research Board Of Ireland Neural Tube Defects Study
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批准号:8351158
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项目类别:
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资助金额:$50.0万
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财政年份:--
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负责人:James Mills
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依托单位:
Chile Fetal Alcohol Study
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批准号:8351195
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项目类别:
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资助金额:$32.4万
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财政年份:--
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负责人:James Mills
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依托单位:
Chile Fetal Alcohol Study
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批准号:7734801
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项目类别:
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资助金额:$1.49万
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财政年份:--
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负责人:James Mills
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依托单位:
Cushing's Disease Whole Exome Sequencing Study
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批准号:10004474
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项目类别:
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资助金额:$14.27万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD-California Birth Defects Study
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批准号:10004476
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项目类别:
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资助金额:$39.52万
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财政年份:--
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负责人:James Mills
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依托单位:
Chile Fetal Alcohol Study
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批准号:8149334
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项目类别:
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资助金额:$28.89万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD Health Research Board Of Ireland Neural Tube Defects Study
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批准号:8941478
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项目类别:
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资助金额:$14.84万
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财政年份:--
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负责人:James Mills
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依托单位:
Iodine and Reproduction
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批准号:10459130
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项目类别:
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资助金额:$14.22万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD-California Birth Defects Study
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批准号:10459129
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项目类别:
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资助金额:$16.16万
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财政年份:--
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负责人:James Mills
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依托单位:
Genetic Factors in Birth Defects
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批准号:8351192
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项目类别:
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资助金额:$50.0万
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财政年份:--
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负责人:James Mills
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依托单位:
Chile Fetal Alcohol Study
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批准号:8553928
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项目类别:
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资助金额:$30.99万
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财政年份:--
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负责人:James Mills
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依托单位:
Genetic Factors in Birth Defects
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批准号:8553925
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项目类别:
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资助金额:$75.02万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD Health Research Board Of Ireland Neural Tube Defects Study
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批准号:8736860
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项目类别:
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资助金额:$20.89万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD-California Birth Defects Study
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批准号:9150193
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项目类别:
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资助金额:$29.13万
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财政年份:--
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负责人:James Mills
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依托单位:
Genetic Factors in Birth Defects
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批准号:10687743
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项目类别:
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资助金额:$10.43万
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财政年份:--
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负责人:James Mills
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依托单位:
NICHD-California Birth Defects Study
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批准号:9348263
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项目类别:
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资助金额:$35.25万
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财政年份:--
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负责人:James Mills
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依托单位:
Genetic Factors in Birth Defects
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批准号:7594248
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项目类别:
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资助金额:$37.39万
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财政年份:--
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负责人:James Mills
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依托单位:
Genetic Factors in Birth Defects
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批准号:7734797
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项目类别:
-
资助金额:$74.42万
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财政年份:--
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负责人:James Mills
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依托单位:
Cushing's Disease Whole Exome Sequencing Study
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批准号:10911731
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项目类别:
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资助金额:$12.33万
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财政年份:--
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负责人:James Mills
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依托单位:
海外基金