Chile Fetal Alcohol Study

我们的研究设计使我们能够确定并跟踪96名怀孕期间每天至少喝4杯酒的妇女。在这些产前大量饮酒的妇女中，有3例死产和1例早产；98名不饮酒的女性没有死产，有两名早产。早产率没有显著差异。暴露组死胎率较高（p = 0.06）。进一步调查显示，暴露人群的死产率（3.1%）显著高于智利报告的人口率（0.45%）（p = 0.019）。我们的数据表明，大量饮酒可能会增加死产的风险，但不会增加早产的风险。

Our study design enabled us to identify and follow 96 women consuming at least 4 drinks/day during pregnancy. In these women with heavy prenatal alcohol use, there were three stillbirths and one preterm delivery; 98 matched nondrinking women had no stillbirths and two preterm births. Preterm rates did not differ significantly. The stillbirth rate was higher in the exposed group (p = 0.06). Additional investigation showed the stillbirth rate in the exposed population (3.1%) was significantly higher (p = 0.019) than the reported Chilean population rate (0.45%). Our data suggest that heavy alcohol consumption may increase the risk for stillbirth but not preterm delivery. Analysis is now complete and a report has been prepared describing the outcomes of the exposed children based on the amount and pattern of maternal alcohol consumption during pregnancy. The data will be reported soon.