Immune correlates of early corticosteroid therapy in Vietnamese children and young adults with dengue

登革热是一种全球重要的传染病。这项研究将试图了解皮质类固醇--一种免疫调节药物--如何影响登革热儿童的免疫反应。这项研究的基础是在越南一家大型医院进行的一项随机对照试验，该试验治疗许多登革热患者。我们希望获得支持该药物进一步临床试验所需的实验室证据，这样我们将提高对登革热的了解。

Dengue is a globally important infectious disease. This study will seek to understand how corticosteroids, an immune modulating class of drug, effect the immune responses in children with dengue. The basis for this study is a randomised controlled trial at a large hospital in Viet Nam that treats many patients with dengue. We expect to obtain the laboratory evidence needed to support further clinical trials of this drug and in doing so we will improve our understanding of dengue.