Integrating HIV and Substance Abuse Prevention for Hispanic Families: La Familia

描述(由申请人提供)：缺乏关于最近和远程应激源(包括移民前应激事件)在拉美裔人口中的影响的研究，仍然需要开发干预措施来解决这些应激源，并减少消极的危险行为，如吸毒和危险的性行为(Avison&Gotlib，1994)。因此，目前存在着一个巨大的心理健康专业人员、学校辅导员、儿科医生和研究人员市场，他们需要为拉美裔青年及其家庭提供有效的行为健康预防干预。尽管许多拉美裔青年面临更高的药物滥用、青少年怀孕、不安全性行为和艾滋病毒的风险(Prado等人，2006年)，但缺乏针对拉美裔青年的以药物滥用和艾滋病毒预防为目标的基于商业证据的做法(Cervantes，Kappos，Duenas&Arellano，2003年)。这项拟议的SBIR第一阶段研究的长期目标是修订Familia Adelante(FA)早期药物干预和预防计划(Cervantes，2005)，纳入艾滋病毒预防成分，从而使Familia Adelante成为有效的商业可用模式计划。通过与专家小组和西班牙裔家庭(n=144)目标人群成员的定性数据收集，这项I期SBIR研究将修订FA计划，以包括艾滋病毒预防成分，并确定设计II期SBIR研究的可行性，该研究将在西班牙裔家庭的多地点随机临床试验样本中测试Familia Adelante修订(FA-R)。在成功完成第二阶段SBIR研究后，BAI的目标是将FA-R用于商业目的，向健康和精神卫生保健提供者、学校精神卫生人员和与拉美裔家庭合作的研究人员推销FA-R。 公共卫生相关性：目前有一个巨大的市场，需要心理健康专业人员、学校辅导员、儿科医生和研究人员，他们需要为拉美裔青年及其家庭提供有效的行为健康预防干预。尽管许多拉美裔青年面临更高的药物滥用、青少年怀孕、不安全性行为和艾滋病毒的风险(Prado等人，2006年)，但缺乏针对拉美裔青年的以药物滥用和艾滋病毒预防为目标的基于商业证据的做法(Cervantes，Kappos，Duenas&Arellano，2003年)。这项拟议的SBIR研究的长期目标是通过纳入HIV预防成分来修订Familia Adelante(FA)早期药物干预和预防计划(Cervantes，2005)，从而使Familia Adelante成为一个有效的、商业上可用的模式计划。这项第一阶段SBIR研究将修订FA计划，以包括艾滋病毒预防部分，并确定设计第二阶段SBIR研究的可行性，该研究将在西班牙裔家庭的多地点随机临床试验样本中测试Familia Adelante修订(FA-R)。

DESCRIPTION (provided by applicant): There is a dearth of research on the affects of recent and remote stressors (including pre- migration stress events) in the Hispanic population and there remains the need for the development of interventions which can address these stressors, and reduce negative risky behavior such as drug use and risky sexual behaviors (Avison & Gotlib, 1994). As such, there currently exists a large market of mental health professionals, school counselors, pediatricians, and researchers who are in need of effective behavioral health prevention interventions for Hispanic youth and their families. Although many Hispanic youth are at increased risk for substance abuse, teen pregnancy, unsafe sexual practices and HIV (Prado et al., 2006), there is a lack of commercially available evidence-based practices for Hispanic youth which target substance abuse and HIV prevention (Cervantes, Kappos, Duenas & Arellano, 2003). The long- term objective of this proposed SBIR Phase I research is to revise the Familia Adelante (FA) early drug intervention and prevention program (Cervantes, 2005) to incorporate an HIV prevention component, so as to make Familia Adelante an effective and commercially available model program. Through qualitative data collection with an expert panel and members of the target population of Hispanic families (n=144), this Phase I SBIR study will revise the FA program to include an HIV prevention component, as well as determine the feasibility of designing a Phase II SBIR study which will test the Familia Adelante-Revised (FA-R) in a multi site randomized clinical trial sample of Hispanic families. Upon successful completion of the Phase II SBIR study, BAI aims at marketing the FA-R for commercial purposes to health and mental health care providers, school mental health personnel and researchers who work with Hispanic families. PUBLIC HEALTH RELEVANCE: There currently exists a large market of mental health professionals, school counselors, pediatricians, and researchers who are in need of effective behavioral health prevention interventions for Hispanic youth and their families. Although many Hispanic youth are at increased risk for substance abuse, teen pregnancy, unsafe sexual practices and HIV (Prado et al., 2006), there is a lack of commercially available evidence- based practices for Hispanic youth which target substance abuse and HIV prevention (Cervantes, Kappos, Duenas & Arellano, 2003). The long-term objective of this proposed SBIR research is to revise the Familia Adelante (FA) early drug intervention and prevention program (Cervantes, 2005) by incorporating an HIV prevention component, so as to make Familia Adelante an effective and commercially available model program. This Phase I SBIR study will revise the FA program to include an HIV prevention component, as well as determine the feasibility of designing a Phase II SBIR study which will test the Familia Adelante-Revised (FA-R) in a multi site randomized clinical trial sample of Hispanic families.