Photomultiplier Chip(TM) for ultra-fast TOF-PET

描述（由申请人提供）：LightSpin Technologies, Inc.提议开发一种能够为TOF-PET应用提供超快速时序分辨率的光电探测器模块。光电探测器模块利用LightSpin的超快速光电倍增管芯片tm技术，该技术能够在大光敏区域（超过10 mm2）内实现低于20 ps的单光子定时抖动，同时保持优异的量子效率（超过50%），线性度和动态范围。这一突破源于LightSpin在半导体单光子探测器和单片集成电子电路方面的创新。光电探测器模块将与快速闪烁体（掺铈溴化镧）耦合，提供最终能力，实现超快速TOF-PET，符合分辨率优于50 ps FWHM。在第一阶段，LightSpin将在光电探测器本身和与闪烁体耦合的简单光电探测器模块中展示良好的定时性能。在第二阶段，LightSpin将开发一个完整的PET探测器相机模块，包括多个光电探测器和一个读出ASIC，以报告入射伽马射线的X、Y、定时和能量。公共卫生相关性：所提出的探测器模块允许比传统PET扫描仪小50倍的辐射剂量，以获得更好的图像。该创新是一种超高速探测器模块，可实现40 ps的飞行时间PET，信噪比提高7倍。

DESCRIPTION (provided by applicant): LightSpin Technologies, Inc., proposes to develop a photodetector module capable of providing ultra-fast timing resolution for TOF-PET applications. The photodetector module exploits LightSpin's ultra-fast Photomultiplier ChipTM technology, which is capable of achieving single-photon timing jitter below 20 ps across large photo-sensitive areas (more than 10 mm2), while maintaining excellent quantum efficiency (above 50%), linearity and dynamic range. The breakthrough stems from LightSpin's innovation in semiconductor single-photon detectors and monolithically integrated electronic circuits. The photodetector module will be coupled to a fast scintillator (cerium-doped lanthanum bromide), providing an ultimate capability to achieve ultra-fast TOF-PET with coincidence resolution better than 50 ps FWHM. In Phase I, LightSpin will demonstrate good timing performance in the photodetector itself and in a simple photodetector module coupled to a scintillator. In Phase II, LightSpin will develop a full PET detector camera module, including multiple photodetectors and a readout ASIC to report X, Y, timing, and energy of incident gamma rays. PUBLIC HEALTH RELEVANCE:The proposed detector module allows a radiation dose 50 times smaller than in conventional PET scanners to give a better image. The innovation is an ultra-fast detector module enabling 40 ps time-of-flight PET, with 7 times better signal-to-noise ratio.