A Real-Time, Minimally Invasive Monitoring System for Early Detection of Shock

描述（由申请人提供）：该项目的总体目标是开发并商业化一种用于患者监测的新型传感器系统，该系统将测量肌肉中的氧气和二氧化碳。这些指标可用于预测失血性休克的早期发作，量化心脏复苏的疗效，提高危重患者的护理标准。为了实现这一目标，将利用新技术制造非常小且高精度的传感器来测量组织中的氧气或二氧化碳。这些传感器不需要现场校准，可以轻松快速地植入组织中。传感器系统将小而坚固，重量只有几盎司，它们将由电池供电。该传感器系统旨在在困难条件下以及在设备齐全的医疗设施中可靠地工作。将在每个级别采取谨慎措施，以确保最佳性能，易用性，并与适用的临床环境紧密集成。这种传感器系统将大大改善危重病人的护理，特别是那些遭受急性创伤的病人。

DESCRIPTION (provided by applicant): The overall goal of this project is to develop and commercialize a new sensor system for patient monitoring that will measure both oxygen and carbon dioxide in the muscle. These measurements can be used to predict the early onset of hemorrhagic shock, quantify the efficacy of cardiac resuscitation, and improve the standard of care for critically ill patients. To accomplish this goal, novel technology will be utilized to make very small and highly accurate sensors for measuring oxygen or carbon dioxide in tissue. These sensors will not require on site calibration and can be easily and quickly implanted in tissue. The sensor systems will be small and robust, weighing only a few ounces and they will be battery operated. The sensor system is intended to perform reliably in the field under difficult conditions as well as in fully equipped medical facilities. Care will be taken at every level to assure optimal performance, ease of use, and tight integration into the applicable clinical environment. This sensor system will substantially improve the care of critically ill patients, particularly those suffering from acute trauma. PUBLIC HEALTH RELEVANCE: This proposal will result in a medical device that will improve the monitoring capabilities for critical care patients and for patients undergoing CPR. The device will accurately monitor oxygen levels in muscle to give an accurate measure of how the circulation is functioning. The product is designed to be used by first responders in field situations, and in the ICU.