Enhancing Community-based Cancer Control in Iowa

描述(由申请人提供)：爱荷华州大学霍尔登综合癌症中心(HCCC)与爱荷华州癌症联盟(ICC)、爱荷华州治疗教育和研究中心(CERT)和爱荷华州研究网络(IERNE)合作，提议开发一项综合计划，为整个爱荷华州的社区癌症控制研究提供基础设施。该计划将利用NCI指定的综合癌症中心(HCCC)、全州癌症控制联盟(ICC)、爱荷华大学CERT和全州家庭医生网络提供的优势，这些家庭医生网络参与了以实践为基础的研究(IERNE)。该计划最初的研究重点将是基于爱荷华州这一领域的势头，了解和解决爱荷华州结直肠癌(CRC)负担方面的差异。作为这一计划的一部分而建立的基础设施然后可以应用于基于社区的研究，以解决其他癌症和与癌症负担相关的生活方式问题(戒烟、肥胖、缺乏体育锻炼和不良饮食习惯)。目前的提案侧重于加强这些合作伙伴提供的研究基础设施，以增强其开展社区研究的能力。这一基础设施将在三个层面得到支持：1)增强我们分析来自不同来源的数据的能力；2)通过鼓励跨学科合作和互动，促进参与癌症控制研究；3)增加爱荷华州艾琳诊所对癌症控制研究的参与。 公共卫生相关性：癌症是美国和爱荷华州的第二大死因。在爱荷华州，就像在整个国家一样，在癌症检测和治疗方面存在着重大的健康差距，那些拥有最少资源的人的结果更差。这笔赠款将在爱荷华州公民之间建立以爱荷华州癌症联盟(致力于减轻爱荷华州癌症负担的组织)、爱荷华州研究网络(以初级保健实践为基础的研究网络)和爱荷华州大学为代表的伙伴关系，旨在了解和解决爱荷华州结直肠癌负担的差异。作为该计划的一部分而建立的基础设施随后将应用于社区研究，以解决其他癌症和与癌症负担相关的生活方式问题(戒烟、肥胖、缺乏体育锻炼和不良饮食习惯)。

DESCRIPTION (provided by applicant): The University of Iowa Holden Comprehensive Cancer Center (HCCC), in collaboration with the Iowa Cancer Consortium (ICC), the Iowa Center for Education and Research on Therapeutics (CERT) and the Iowa Research Network (IRENE), propose development of a comprehensive program that will provide the infrastructure to support community-based, cancer control research across Iowa. This program will take advantage of strengths provided by an NCI- designated Comprehensive Cancer Center (HCCC), a statewide cancer control consortium (ICC), the University of Iowa CERT, and a statewide network of family physicians which has participated in practice-based research (IRENE). The initial research focus of this program will be geared toward understanding and addressing the disparities in the burden of colorectal cancer (CRC) across Iowa based on momentum in this area across the state of Iowa. The infrastructure built as part of this program can then be applied to community-based research that addresses other cancers and life-style issues relating to cancer burden (tobacco cessation, obesity, lack of physical activity, and poor dietary practices). The current proposal focuses on strengthening the research infrastructure provided by these partners to enhance their ability to perform community-based research. This infrastructure will be supported at three levels: 1) enhancing our ability to analyze data from different sources, 2) facilitating participation in cancer control research by encouraging interdisciplinary collaboration and interaction, and 3) increasing the participation in cancer control research by IRENE practices across Iowa. PUBLIC HEALTH RELEVANCE: Cancer is the second leading cause of death in both the United States and the State of Iowa. In Iowa, as in the nation as a whole, there are major health disparities in cancer detection and treatment, with worse outcomes for those with the fewest resources. This grant will build a partnership among the citizens of Iowa, represented by the Iowa Cancer Consortium (an organization dedicated to reducing the burden of cancer in Iowa), the Iowa Research Network (a primary care practice-based research network), and the University of Iowa that will be geared toward understanding and addressing the disparities in the burden of colorectal cancer in Iowa. The infrastructure built as part of this program will then be applied to community-based research that addresses other cancers and life-style issues relating to cancer burden (tobacco cessation, obesity, lack of physical activity, and poor dietary practices).