Biostatistics with a focus on cardiovascular health and minority populations

描述（由申请人提供）： 我们请求支持一个新的3年NHLBI/NCRR本科培训补助金T-15，旨在鼓励高级本科生和开始研究生考虑生物统计学职业。我们提出了一个为期6周的住宅夏季培训计划，在合作生物统计学定量为导向的本科生和开始研究生谁是在健康科学感兴趣。该计划强调了在心血管健康和少数民族人群的多学科研究背景下生物统计学的协作性质。具体目标是：（1）向受训者介绍在令人信服的科学问题和真实的数据背景下的基本生物统计方法;（2）向受训者传授自己解决这些问题所需的分析和计算机技能;（3）在协作小组环境下积极让受训者参与个人项目;以及（4）除了提供在生物统计学领域进一步培训和就业的机会外，还教育学员生物统计学思维在合作研究中的作用。我们预计在第一年培训20名学生，在第二年和第三年各培训24名学生（三年共培训68名学员）。我们提出了一个4学分的计划，包括一个综合的3学分课程介绍生物统计学和1学分的合作生物统计学研讨会。该计划由具有基于人口的研究，临床试验，适应性设计，药物安全，卫生服务研究，风险因素减少，少数民族健康，遗传学，人口统计学，调查抽样，地理编码和生物信息学领域专业知识的合作生物统计学家授课。我们的合作者在几个大型NHLBI资助的心血管疾病，肺炎和肺栓塞试验，以及注册和人口为基础的研究参与临床导师。学生将在计算机实验室创建自己的案例研究笔记本。在研讨会上，学生将在协作团队中进行互动，并根据NHLBI资助的研究，健康黑人家庭项目或阿勒格尼县卫生局的心血管数据集开发个人海报演示。该方案将在每年年底由重点小组进行评估，并根据咨询委员会的建议进行修订。该计划将突出统计思维在重要的心血管项目中的作用，如果成功，将扩大可能考虑进一步培训生物统计学的学生人数。通过专注于从我们自己的研究中得出的令人信服的生物医学例子，以及直观的实践活动，该计划可以吸引未来的学生到生物统计学领域（1）具体的例子表明，生物统计学是生物医学研究的一个有趣的组成部分;（2）临床合作者加强生物统计贡献的价值;（3）学生看到自己在做这样的工作。 (End摘要）

DESCRIPTION (provided by applicant): We request support for a new 3-year NHLBI/NCRR undergraduate training grant T-15 designed to encourage advanced undergraduate and beginning graduate students to consider careers in biostatistics. We propose a 6-week residential summer training program in collaborative biostatistics for quantitatively- oriented undergraduate and beginning graduate students who are interested in the health sciences. This program highlights the collaborative nature of biostatistics within the context of multidisciplinary research studies in cardiovascular health and minority populations. The specific aims are to (1) introduce trainees to basic biostatistical methods in the context of compelling scientific questions and real data; (2) teach trainees the analytic and computer skills necessary to address these questions themselves; (3) actively involve trainees in individual projects within a collaborative group setting; and (4) educate trainees about the role of biostatistical thinking in collaborative research in addition to opportunities for further training and employment in the field of biostatistics. We anticipate training 20 students in Year 1 and 24 students each in years 2 and 3 (a total of 68 trainees in 3 years). We propose a 4-credit program comprised of an integrated 3-credit course in Introductory Biostatistics and a 1-credit Collaborative Biostatistics Seminar. This program is taught by collaborative biostatisticians with expertise in the areas of population-based studies, clinical trials, adaptive designs, medication safety, health services research, risk factor reduction, minority health, genetics, demography, survey sampling, geocoding, and bioinformatics. Our collaborators on several large NHLBI-funded trials in cardiovascular disease, pneumonia, and pulmonary embolism as well as registry and population-based studies participate as clinical mentors. Students will create their own case study notebooks in the computer laboratory. In the seminar, students will interact in collaborative teams and develop individual poster presentations based on cardiovascular datasets from NHLBI-funded studies, the Healthy Black Family project, or the Allegheny County Health Department. The program will be evaluated using focus groups at the end of each year, and revised according to suggestions of the Advisory Committee. This program will highlight the role of statistical thinking in important cardiovascular projects and, if successful, expand the population of students who might consider further training in biostatistics 7 RELEVANCE: By focusing on compelling biomedical examples drawn from our own research, and intuitive, hands-on activities, this program could attract prospective students to the field of biostatistics by (1) concrete examples demonstrating that biostatistics is an interesting component of biomedical research; (2) clinical collaborators reinforcing the value of biostatistical contributions; and (3) students seeing themselves doing such work. (End of Abstract)