Academic Training in Rheumatology

描述（由申请人提供）：医学面临的最大挑战是将当代科学的最新发展带到床边。这一挑战只能通过培养一批能够开展高质量研究的研究人员来应对，这些研究旨在加强面向患者的调查。因此，这项培训资助提案寻求支持个人（医学博士、医学博士/博士或博士）在生物医学科学领域的职业生涯，因为它与风湿病学有关。该项目以风湿病学部门为基础，拥有30名教职员工，其中包括14名联邦资助的研究人员和活跃的临床和基础研究项目。风湿病学部门，包括其相关诊所，是加州大学洛杉矶分校大卫·格芬医学院的一部分，包括临床和生物医学科学系。主要的指导老师不仅来自医学系，也来自病理科、微生物/免疫/摩尔系。遗传学、药理学和公共卫生学院。广泛的专业领域包括自身免疫、基础免疫学、临床干预和治疗、基因组学、基因表达和治疗、卫生质量、经济学和政策。该项目得到了核心设施、学术课程和PI发起的校园范围内的转化免疫学项目的良好支持。人们相信，这个风湿病学项目提供了独特的资源，并将继续扩大对研究有职业兴趣的个人池，因为它与亚专业相关，这个池太小，无法满足未来几十年分子医学越来越多地应用于临床的要求。

DESCRIPTION (provided by applicant): The greatest challenge to medicine is to bring to the bedside the latest developments in contemporary science. This challenge can only be met by developing a cadre of investigators who can conduct high quality research that is geared to strengthen patient-oriented investigations. Hence, this training grant proposal seeks support to prepare individuals (MD, MD/PhD, or PhD) for a career in biomedical science as it relates to Rheumatology. The program is based in a large Division of Rheumatology with 30 faculty members including 14 federally funded investigators and active clinical and basic research programs. The Division of Rheumatology, including its related clinics, is part of the David Geffen School of Medicine at UCLA with its clinical and biomedical science departments. The primary faculty advisors come not only from divisions within the Department of Medicine but also from the Departments of Pathology, Microbiol/lmmunol /Mol. Genetics, Pharmacology, and School of Public Health. The broad areas of expertise covered include autoimmunity, basic immunology, clinical intervention and therapeutics, genomics, gene expression and therapy, and health quality, economics and policy. The program is well supported by core facilities as well as by academic courses and a campus-wide translational immunology program initiated by the PI. It is believed that this Rheumatology program provides unique resources and will continue to enlarge the pool of individuals with a career interest in research as it relates to the subspecialty, a pool that is far too small to meet the requirements of the next decades as molecular medicine is increasingly applied in the clinic. The first year of the fellowship program consists of extensive clinical training and is funded through local sources. During the 2nd and 3rd years, the trainee will work in his/her chosen area of research, while maintaining sufficient clinical activity to fulfill the specialty board requirements. The trainees desiring and/or requiring experience to make the transition to academic investigator will be funded through the proposed T32 and for those who elect PhD or Master's curricula, through the UCLA STAR (Specialty Training in Advanced Research) program. This application seeks support for the critical 2-year period which transitions the trainee from her/his initial clinical rheumatology experience to a career in academic rheumatology. The application also seeks two-year training support for non-clinical postdoctoral trainees who desire to train in Rheumatology to develop an academic research career in the subspecialty.