Post-Doctoral Research Training in Genetic Epidemiology

描述(由申请者提供)：这个修订后的博士后研究培训计划的主要目标是培养基因流行病学方面的尖端独立科学家和未来的研究领导者。我们建议在多学科环境下进行这项工作，重点是心血管疾病(CVD)和心血管危险因素以及其他与心、肺和血液疾病相关的复杂特征的实质性应用方向。我们认为，华盛顿大学的研究环境非常适合开展遗传流行病学和心血管遗传流行病学的研究。这一新计划的基石是强调在经验丰富的导师的监督下，对每一名受训者进行高强度和持续的个性化培训。事实上，强调个性化培训是其标志之一。它的核心是由项目总监、学员导师(S)和学员为每个学员开发的个性化培训路径。个别学员的资讯科技计划将反映其教育背景、以往的研究经验(如有的话)、学员的特定研究兴趣，以及课程需要和他/她所需的研究经验类别。项目主任和参加培训的教师倡导的研究和培训理念的重点是清楚地了解遗传流行病学的概念、原理和方法，以研究心血管疾病和相关复杂特征所依据的生理和病理生理过程。我们正在申请第一年2个名额，第二年3个，之后4个名额的资金。我们的建议通过将精心挑选的教学培训与更多地强调直接动手研究和授权写作经验相结合来迎接挑战。这一培训计划的一大优势在于，整个DBBS庞大的现有资源和丰富的跨学科培训环境，以及GEMS遗传流行病学硕士学位培训计划，都可供该计划的所有博士后学员使用。拟议的博士后研究培训计划渴望培养出未来的遗传流行病学家，在目前的市场上，从事心血管和其他生物医学研究的需求很大。华盛顿大学的科研培训环境非常出色，该校还设有单独的博士后事务办公室，负责照顾博士后学员和他们的特殊需求。

Description (provided by applicant): The primary objective of this revised post-doctoral research training program is to produce cutting edge independent scientists and future research leaders in genetic epidemiology. We are proposing to do this in a multidisciplinary setting and with emphasis on substantive applied orientation in cardiovascular disease (CVD) and CVD risk factors and other complex traits related to heart, lung, and blood disorders. We believe that the research environment at Washington University is outstanding for carrying out research in genetic epidemiology and cardiovascular genetic epidemiology. The cornerstone of this new program is its emphasis on intense and sustained individualized training of each trainee under the supervision of an experienced preceptor. Indeed, emphasis on individualized training is one of its hallmarks. Its centerpiece is an Individualized Training Pathway (ITP) developed for each trainee by the Program Director, the trainee's preceptor(s), and the trainee. An individual trainee's ITP will reflect his/her educational background, the previous research experience if any, the particular research interests of the trainee, and will address the curriculum needs as well as the type of research experience he/she needs. The focus of the research and training philosophy advocated by the Program Director and the participating preceptors is a clear understanding of the concepts, principles, and methods of genetic epidemiology necessary for investigating the physiological and pathophysiological processes that underlie CVD and related complex traits. We are requesting funds for 2 slots in the first year, 3 in the second, and 4 thereafter. Our proposal rises to the challenge by blending and integrating carefully chosen didactic training with greater emphasis on a direct hands-on research and grant writing experience. One of the great strengths of this training program is that the vast established resources and rich interdisciplinary training environment of the entire DBBS, as well as that of the GEMS masters degree training program in genetic epidemiology are available to all post-doctoral trainees in this program. The proposed post-doctoral research training program aspires to produce future genetic epidemiologists in much demand in the current market place for pursuing cardiovascular and other biomedical research. The research training environment at Washington University is outstanding, which also has a separate Office of Post Graduate Affairs to look after postdoctoral trainees and their special needs.