Enhancement of Two Key Research Programs within the Sylvester Cancer Center

描述（由申请人提供）：西尔维斯特癌症中心（西尔维斯特）是一个以会员制为基础的矩阵组织，汇集了来自迈阿密大学两所不同学校18个不同部门的121名成员和133名附属教师研究人员，进行多学科癌症研究。跨学科的翻译研究是通过该中心的七个多学科研究计划（MRP）促进。目前，国家癌症倡议为70个项目提供的资金总额为192972.01亿美元。继续发展西尔维斯特的病毒肿瘤学和生物行为肿瘤学MRP是该中心的最高优先事项之一。每个解决独特的社区需求，通过凝聚力的研究主题，利用教师的优势。这两个方案都是相对较小的方案，它们确定了可以通过征聘最好地填补的关键差距。我们建议招聘两名候选人-每个项目一名。本申请中提到的调查人员是在去年秋季该中心会员务虚会的战略规划后确定的，并且在招聘因大学的财务挑战而暂停时已经对该中心进行了初步访问。幸运的是（对西尔维斯特来说）他们仍然是可用的，并且非常感兴趣。他们的研究发展的详细计划已经完成，评估总体成功的计划也已经完成。西尔维斯特的研究预算高度依赖于筹款、捐赠、机构支持和国家资助。所有这四个支持来源都受到了当前经济衰退的不利影响。这一P30的供资将为加强该中心七项管理资源规划中的两项提供关键支助。作为一个区域资源，该中心对一个主要集水区有直接影响，该集水区包括居住在佛罗里达东南部三个县沿着125英里海岸线的540万人。由于其以旅游为导向和以增长为基础的经济，该地区受到当前经济衰退的打击尤为严重。西尔维斯特在医学院也是高度互动的。所有的教师招聘都是与最合适的学术部门联合进行的。与其他中心和机构的合作也比比皆是，包括跨学科干细胞研究所，迈阿密人类基因组研究所和迈阿密CTSA倡议。因此，加强这两个MRP将加强西尔维斯特和这个学术健康科学中心。

DESCRIPTION (Provided by the applicant): The Sylvester Cancer Center (Sylvester) is a membership-based, matrix organization which brings together 121 members and 133 affiliate faculty investigators from 18 different departments in two different schools of the University of Miami to conduct multidisciplinary cancer research. Interdisciplinary translational research is facilitated through the center's seven multidisciplinary research programs (MRPs). Total NCI funding is currently $19,297,201 million for 70 projects. Continuing development of Sylvester's Viral Oncology and Bio-behavioral Oncology MRPs are among the highest priorities of the Center. Each address unique community needs through cohesive research themes that take advantage of faculty strengths. Both are relatively small programs which have identified critical gaps that can be best filled through recruitment. We are proposing two candidates for recruitment - one into each of these Programs. The investigators named in this application were identified following strategic planning at the Center's membership retreat in the fall of last year, and had already made initial visits to the Center when recruiting was suspended due to financial challenges in the University. Fortunately (for Sylvester) they are still available and highly interested. Detailed plans for development of their research have been completed as has a plan for evaluation of overall success. The Sylvester research budget is highly dependent on fundraising, endowment, institutional support, and State funding. All four of these sources of support have been adversely impacted by the current recession. Funding of this P30 would provide critical support for strengthening two of the Center's seven MRPs. As a regional resource, the Center has a direct impact on a primary catchment area that includes 5.4 million people living along 125 miles of coastline in the three counties of southeast Florida. Because of its tourist oriented and growth based economy, this area has been particularly hard hit by the current recession. Sylvester is also highly interactive within the School of Medicine. All faculty recruitment is done jointly with the most appropriate academic department. Collaborations with other centers and institutes also abound, including the Interdisciplinary Stem Cell Institute, the Miami Institute for Human Genomics and the Miami CTSA initiative. It follows that enhancing these two MRPs will strengthen Sylvester and this Academic Health Science Center.