Enhancement of Two Key Research Programs within the Sylvester Cancer Center

加强西尔维斯特癌症中心的两个关键研究项目

• 批准号: 7860786
• 负责人: W JARRARD GOODWIN
• 金额: $ 73.64万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-29 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7860786
• 关键词: Address; Adult; African American; Area; Attention; B-Lymphocytes; Behavioral; Behavioral Medicine; Biometry; Budgets; Burkitt Lymphoma; Cancer Burden; Cancer Center; Cancer Control; Cancer Etiology; Cancer Patient; Caregivers; Catchment Area; Cervix carcinoma; Clinic; Clinical; Clinical Psychology; Cognitive; Collaborations; Communities; Community Clinical Oncology Program; Complement; County; Developed Countries; Developing Countries; Development; Development Plans; Disease; EBV-associated disease; Emerging Technologies; Endowment; Epidemiology; Equilibrium; Evaluation; Event; Faculty; Family member; Fatigue; Florida; Focus Groups; Funding; Genes; Genomics; Goals; Growth; Health; Health Psychology; Health Sciences; Health behavior change; Hepatitis C virus; Herpesviridae; Hispanics; Host Defense; Human; Human Herpesvirus 8; Human Papillomavirus; Human T-lymphotropic virus 1; Immune; Immune system; Incidence; Institutes; Interdisciplinary Study; Interferons; International; Investigation; Kaposi Sarcoma; LMP1; Late Effects; Lead; Life; Longevity; Malignant Neoplasms; Medical Oncology; Memory; Minority; Modeling; Modification; Mono-S; Names; Neurocognitive; Neurosciences; Obesity; Oncogenes; Outcome; Palliative Care; Pathology; Pathway interactions; Patients; Pediatric Oncology; Personality; Phosphorylation; Physical Fitness; Physicians; Physiology; Population Heterogeneity; Prevalence; Prevention; Prevention strategy; Primary carcinoma of the liver cells; Process; Production; Proteins; Quality of life; Race; Recruitment Activity; Regulation; Research; Research Infrastructure; Research Personnel; Resources; Role; Schools; Scientist; Source; Specimen; Stem cells; Strategic Planning; Stress; Symptoms; System; T-Cell Leukemia; Technology Assessment; Therapeutic Intervention; Training; Translating; Translational Research; Translations; Ubiquitination; Universities; Viral; Viral Cancer; Virus; Virus Diseases; Visit; Weight; Work; anticancer research; base; biobehavior; cancer care; cancer type; childhood cancer survivor; cognitive behavior therapy; disorder prevention; falls; improved; interest; medical schools; medically underserved population; member; multidisciplinary; neuroimaging; neuroimmunology; new therapeutic target; novel; oncology; population based; prognostic; programs; racial and ethnic disparities; ranpirnase; research to practice; response; social; socioeconomics; success; survivorship; symptom management; treatment effect; tumor; tumorigenesis; virus host interaction

DESCRIPTION (Provided by the applicant): The Sylvester Cancer Center (Sylvester) is a membership-based, matrix organization which brings together 121 members and 133 affiliate faculty investigators from 18 different departments in two different schools of the University of Miami to conduct multidisciplinary cancer research. Interdisciplinary translational research is facilitated through the center's seven multidisciplinary research programs (MRPs). Total NCI funding is currently $19,297,201 million for 70 projects. Continuing development of Sylvester's Viral Oncology and Bio-behavioral Oncology MRPs are among the highest priorities of the Center. Each address unique community needs through cohesive research themes that take advantage of faculty strengths. Both are relatively small programs which have identified critical gaps that can be best filled through recruitment. We are proposing two candidates for recruitment - one into each of these Programs. The investigators named in this application were identified following strategic planning at the Center's membership retreat in the fall of last year, and had already made initial visits to the Center when recruiting was suspended due to financial challenges in the University. Fortunately (for Sylvester) they are still available and highly interested. Detailed plans for development of their research have been completed as has a plan for evaluation of overall success. The Sylvester research budget is highly dependent on fundraising, endowment, institutional support, and State funding. All four of these sources of support have been adversely impacted by the current recession. Funding of this P30 would provide critical support for strengthening two of the Center's seven MRPs. As a regional resource, the Center has a direct impact on a primary catchment area that includes 5.4 million people living along 125 miles of coastline in the three counties of southeast Florida. Because of its tourist oriented and growth based economy, this area has been particularly hard hit by the current recession. Sylvester is also highly interactive within the School of Medicine. All faculty recruitment is done jointly with the most appropriate academic department. Collaborations with other centers and institutes also abound, including the Interdisciplinary Stem Cell Institute, the Miami Institute for Human Genomics and the Miami CTSA initiative. It follows that enhancing these two MRPs will strengthen Sylvester and this Academic Health Science Center.

描述（由申请人提供）：西尔维斯特癌症中心（Sylvester）是一个以会员制为基础的矩阵组织，汇集了来自迈阿密大学两个不同学院的 18 个不同部门的 121 名成员和 133 名附属教职人员研究人员，开展多学科癌症研究。该中心的七个多学科研究项目（MRP）促进了跨学科转化研究。 NCI 目前为 70 个项目提供的资金总额为 192,972.01 亿美元。西尔维斯特病毒肿瘤学和生物行为肿瘤学 MRP 的持续开发是该中心的最高优先事项之一。每个项目都通过利用教师优势的有凝聚力的研究主题来满足独特的社区需求。这两个项目都相对较小，但都发现了可以通过招聘来最好填补的关键差距。我们提议招聘两名候选人 - 每个项目各一名。本申请中指定的调查人员是在去年秋天该中心会员务虚会的战略规划后确定的，并且在由于大学财务困难而暂停招募时已经对该中心进行了初步访问。幸运的是（对于西尔维斯特来说）他们仍然有空并且非常感兴趣。他们的研究发展的详细计划已经完成，评估总体成功的计划也已经完成。西尔维斯特研究预算高度依赖于筹款、捐赠、机构支持和国家资助。所有这四个支持来源都受到当前经济衰退的不利影响。该 P30 的资金将为加强该中心七个 MRP 中的两个提供关键支持。作为区域资源，该中心对主要集水区产生直接影响，该集水区包括居住在佛罗里达州东南部三个县 125 英里海岸线沿岸的 540 万人。由于其以旅游为导向和以增长为基础的经济，该地区受到当前经济衰退的打击尤为严重。西尔维斯特在医学院内也具有高度互动性。所有教师招聘都是与最合适的学术部门联合完成的。与其他中心和机构的合作也比比皆是，包括跨学科干细胞研究所、迈阿密人类基因组学研究所和迈阿密 CTSA 倡议。因此，加强这两项 MRP 将加强西尔维斯特和这个学术健康科学中心。