Cell and Molecular Biology Core

细胞与分子生物学(CMB)核心的目标是增强和扩展质量和范围 个人研究项目，通过提供获得分子技术和措施的途径，将产生 对听力和听力障碍的分子基础的洞察。为了实现这一目标，中巴核心 有四个领域的具体目标：发展、教育、合作和服务。在……里面 发展，招商局将为个人调查人员带来新的方法和途径，并开发 技术和数据库，方便鼠标模型的使用。在教育方面，中巴将提供 向个别调查员提供有关方法学新进展的信息，培训个别调查员的工作人员 在常规和新的分子方法论方面，为密歇根大学的集中化提供了一座桥梁 为新颖和先进的方法提供便利，并每月举行核心讨论小组会议，与 外部特定主题的专家介绍新的方法和途径，分享经验和问题 和成功，并发展新的富有成效的合作。最后一个目标将在#年扩大 合作，CMB将带来新的研究人员来研究听力和平衡研究， 引入外部专家以获得新的方向和方法，并为导致以下问题的讨论提供一种形式 研究的新领域和新方向。对于服务，中巴将提供最先进的支持 形态和分子评估，为形态和分子的整合提供帮助 评估，提供标准数据库，并在实验设计和 对结果的解释。 CMB核心还将与生理核心和交付核心密切合作，以协调 动物在分子和系统水平上的生理和形态特征 加强我们对听力的理解，并确定将预防和治疗的分子干预措施 听力损失。

The goal of the Cell & Molecular Biology (CMB) Core is to enhance and extend the quality and scope of individual research projects, by providing access to molecular technologies and measures that will yield insights into the molecular basis for hearing and hearing impairment. To achieve this goal the CMB Core has Specific Aims that fall into four areas: Development, Education, Collaboration and Service. In Development, the CMB will bring new methods and approaches to individual investigators and develop technology and data bases to facilitate use of the mouse model. In Education, the CMB will provide information on new advances in methodology to individual investigators, train staff of individual investigators in both routine and novel molecular methodologies, provide a bridge to centralized University of Michigan facilities for novel and advanced methodologies, and hold monthly meetings of Core Discussion Group with outside experts on specific topics to introduce new methods and approaches, share experiences, problems and successes and develop new productive collaborations. This last goal will be expanded In Collaborations, in which the CMB will bring new investigators to the study of hearing and balance research, bring in outside experts for new directions and approaches, and provide a format for discussions leading to new areas and directions of research. For Service, the CMB will provide state-of-the-art support for morphological and molecular assessments, provide assistance in integration of morphological and molecular assessments, provide normative data bases and provide assistance in experimental design and interpretation of results. The CMB Core will also work closely with the Physiology Core and the Delivery Core to coordinate physiological and morphological characterization of animals at both the molecular and systems level to enhance our understanding of hearing and to define molecular interventions that will prevent and treat hearing loss.