Cancer Imaging

癌症成像设施共享资源是一个广泛的服务中心，支持一系列研究 癌症社区。该设施由一个小型动物成像中心、一个回旋中心和一个 探索化学核心，支持临床前和临床研究。主实验室提供光学设备 成像方式，包括生物发光和荧光成像系统以及两种 用于组织和整体切片的MicroCT扫描仪、超声波扫描仪和冷冻机系统 动物。主实验室外是一个装有7特斯拉、30厘米横孔磁共振系统的房间， MicroSPECT-CT扫描仪和MicroPET扫描仪。回旋加速器设施位于卢卡斯附近 建立了一个将示踪剂安全运送到克拉克中心和核中心的系统 医学部。额外的工作台空间可用于开发新的成像仪器和 在动物身上做手术。手术区有手术照明和便携式手术。 显微镜。与成像设施相邻的是两个房间，用于安置动物，这些动物要么 注射了放射性核素以进行microPET或microSPECT成像，或感染了选定的生物安全 2级病原体。一个计算机实验室和行政办公室也位于核心空间内。 共享资源由两名全职博士级科学家管理，他们为用户提供以下方面的培训 每个系统，以及关于实验设计、选择适当的成像模式和 帮助进行数据分析。共享资源还提供联网的计算机服务器以允许数据 存储和访问，以及完整的数据备份和归档。该资源旨在提供完整的 小动物成像模式集中在一个位置，使用户能够利用 在他们的实验中，每种模式的优势。我们有一个培训计划，使用户能够 运行他们自己的实验，尽管共享资源员工和 兽医，如果有必要的话。克拉克中心附近建造了一个新的鼠标屏障设施， 将在这个屏障内建立第二个小动物设施，复制现有的仪器 当前设施和两个成像设施将并行运行，从而允许对两者进行成像 人口。对这一共享资源的学术监督是由分子成像的教员提供的 由克里斯托弗·康塔格博士和萨姆·甘布尔博士领导的斯坦福大学(Stanford)项目。

The Cancer Imaging Facility Shared Resource is a broad service center that supports a range of research in the cancer community. The facility is comprised of a small animal imaging center, a cyclotron center and a probe chemistry core that supports both preclinical and clinical research. The main lab offers optical imaging modalities, including bioluminescence and fluorescence imaging systems, as well as two MicroCT scanners, an ultrasound scanner and cryotome systems for sectioning both tissues and whole animals. Off the main laboratory are rooms housing a 7 Tesla, 30cm horizontal bore MRI system, a MicroSPECT-CT scanner and MicroPET scanners. The cyclotron facility is located nearby in the Lucas center and a system is in place for the safe transport of tracers to the Clark Center and the Nuclear Medicine Department. Additional bench space is available for developing new imaging instruments and for performing procedures on animals. The surgical area has surgical lighting and a portable surgical microscope. Adjacent to the imaging facility are two rooms for housing animals that have either been injected with radionuclides for MicroPET or MicroSPECT imaging, or have been infected with select biosafety level 2 pathogens. A computer lab and administrative offices are also located within the core space. The Shared Resource is managed by two full-time PhD-level scientists, who provide training to users on each of the systems, as well as advice on experiment design, choice of appropriate imaging modality and help with data analysis. The Shared Resource also provides a networked computer server to allow data storage and access, with full data backup and archiving. This resource aims to provide a full array of small animal imaging modalities in a centralized location, allowing users to take advantage of the strengths of each modality within their experiments. We have a training program that enables users to run their own experiments, although assistance is available from both the Shared Resource staff and veterinarians, as necessary. With the building of a new mouse barrier facility adjacent to the Clark Center, a second small animal facility will be created within this barrier, duplicating the instruments present in the current facility, and the two imaging facilities will then run in parallel allowing imaging of the two populations. Academic oversight of this Shared Resource is provided by faculty in the Molecular Imaging Program at Stanford (MIPS), headed by Drs. Christopher Contag and Sam Gambhir.