Virology Core
Virology Core
批准号:
7929999
负责人:
Andrew P Rice
金额:
$21.93万
依托单位国家:
美国
项目类别:
财政年份:
2010
资助国家:
美国
项目状态:
已结题
起止时间:
2010-08-04 至 2015-07-31
关键词:
AIDS/HIV problemAcquired Immunodeficiency SyndromeAntigensAreaArtsBiologicalBiological AssayClinicalDNADetectionDevelopmentDrug IndustryFosteringFutureGoalsHIVHIV InfectionsHIV-1HeadHumanIndividualInfectionLaboratoriesMedicineMolecularPathogenesisPatientsPreventionProcessRNAReagentReporterResearchResearch ActivityResearch PersonnelResearch Project GrantsResearch SupportRiceSamplingServicesSpecimenSupervisionTexasTrainingTranslational ResearchUnited StatesViralVirusWorkbasecatalystcollegecostexperiencelaboratory facilitymacrophagemembernovelprogramsvirology
中文摘要
病毒学核心的总体目标是加强艾滋病毒和艾滋病的研究!在贝勒医学院和休斯顿大学提供全面的最先进的病毒学分析和服务。病毒学中心还将向CFAR艾滋病毒/艾滋病研究人员提供其专门的BSL2/2+实验室设施,并培训他们如何正确使用这些设施。核心小组由安德鲁·p·赖斯(Andrew P. Rice)博士领导,他是一名从事艾滋病毒研究的分子病毒学家,有20多年的经验。Edward Siwak博士,副核心董事,经验丰富的经理,负责核心的日常监督。核心还包括一名经验丰富的工作人员,他们在核心进行的分析中具有特定的专业知识。核心的一个主要目标是通过向CFAR研究人员宣传我们提供试剂(如病毒株、报告病毒、原代人巨噬细胞)和开发适合个人用户需求的检测方法的能力来促进艾滋病毒研究。目前主要的病毒学核心服务包括:(1)基于pcr的HIV-1 RNA、DNA和细胞mrna检测;(2) p24抗原检测;(3)处理、储存和运送HIV感染患者的标本和其他生物样品;(4)培训和使用BSL2/2+设施。最后,
英文摘要
The overall goal of the Virology Core is to enhance HIV and AIDS research! at Baylor College of Medicine and UTHouston by providing comprehensive state-of-the-art virological assays and services. The Virology Core will also make available its specialized BSL2/2+ laboratory facilities to CFAR HIV/AIDS researchers and train them in the proper usage of the facilities. The Core is headed by Dr. Andrew P. Rice, who has over 20 years' experience as a molecular virologist working on HIV. Dr. Edward Siwak, Associate Core Director, an experienced manager, is responsible for the day-to-day supervision of the Core. The Core also includes an experienced staff with specific expertise in the assays performed by the Core. A major goal of the Core is to foster HIV research through publicizing to CFAR investigators our ability to provide reagents (e.g., viral strains, reporter viruses, primary human macrophages) and develop assays tailored to individual user's needs. Current major Virology Core services include: (1) PCR-based assays for HIV-1 RNA and DNA and cellular mRNAs; (2) p24 antigen assays; (3) processing, storage and shipment of specimens and other biological samples from patients with HIV infection; and (4) training and usage of BSL2/2+ facilities. Finally,
the Virology Core has a program in place to evaluate annually the current and future needs of CFAR investigators and provide them with new assays and services as needed for clinical, basic, and translational research projects.
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Developmental Core B
-
批准号:10609476
-
项目类别:
-
资助金额:$28.9万
-
财政年份:2021
-
负责人:Andrew P Rice
-
依托单位:
Developmental Core B
-
批准号:10397170
-
项目类别:
-
资助金额:$178.53万
-
财政年份:2021
-
负责人:Andrew P Rice
-
依托单位:
Imaging-base Automated Screen for Compounds that Induce P-TEFb
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批准号:9352533
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项目类别:
-
资助金额:$23.78万
-
财政年份:2017
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负责人:Andrew P Rice
-
依托单位:
Role of NEAT1 lncRNA in HIV replication
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批准号:9292251
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项目类别:
-
资助金额:$19.81万
-
财政年份:2016
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负责人:Andrew P Rice
-
依托单位:
Role of P-TEFB in HIV latency
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批准号:8841469
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项目类别:
-
资助金额:$23.65万
-
财政年份:2014
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负责人:Andrew P Rice
-
依托单位:
Mechanisms of Action of Novel HIV Rev Co-factors
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批准号:8843222
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项目类别:
-
资助金额:$23.68万
-
财政年份:2014
-
负责人:Andrew P Rice
-
依托单位:
Mechanisms of Reactivation of Latent HIV by HDAC Inhibitors
-
批准号:8786930
-
项目类别:
-
资助金额:$23.48万
-
财政年份:2014
-
负责人:Andrew P Rice
-
依托单位:
Administrative
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批准号:8711163
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项目类别:
-
资助金额:$29.58万
-
财政年份:2014
-
负责人:Andrew P Rice
-
依托单位:
P-TEFb and HIV Latency
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批准号:8685494
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项目类别:
-
资助金额:$36.78万
-
财政年份:2013
-
负责人:Andrew P Rice
-
依托单位:
Identification of novel co-factors for HIV Tat and Rev as therapeutic targets
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批准号:8505377
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项目类别:
-
资助金额:$18.39万
-
财政年份:2012
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负责人:Andrew P Rice
-
依托单位:
Identification of novel co-factors for HIV Tat and Rev as therapeutic targets
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批准号:8401302
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项目类别:
-
资助金额:$23.48万
-
财政年份:2012
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负责人:Andrew P Rice
-
依托单位:
Effects of cocaine on miRNAs that regulate HIV-1 replication
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批准号:8076744
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项目类别:
-
资助金额:$28.29万
-
财政年份:2010
-
负责人:Andrew P Rice
-
依托单位:
Effects of cocaine on miRNAs that regulate HIV-1 replication
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批准号:8246514
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项目类别:
-
资助金额:$28.29万
-
财政年份:2010
-
负责人:Andrew P Rice
-
依托单位:
Structure and function of influenza A virus PDZ-binding motif
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批准号:8072192
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项目类别:
-
资助金额:$19.0万
-
财政年份:2010
-
负责人:Andrew P Rice
-
依托单位:
Effects of cocaine on miRNAs that regulate HIV-1 replication
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批准号:8010507
-
项目类别:
-
资助金额:$29.17万
-
财政年份:2010
-
负责人:Andrew P Rice
-
依托单位:
Structure and function of influenza A virus PDZ-binding motif
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批准号:7989324
-
项目类别:
-
资助金额:$23.03万
-
财政年份:2010
-
负责人:Andrew P Rice
-
依托单位:
Identification of novel HIV-1 co-factors
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批准号:7767655
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项目类别:
-
资助金额:$19.0万
-
财政年份:2009
-
负责人:Andrew P Rice
-
依托单位:
Identification of novel HIV-1 co-factors
-
批准号:7680451
-
项目类别:
-
资助金额:$23.03万
-
财政年份:2009
-
负责人:Andrew P Rice
-
依托单位:
Virology Core
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批准号:7683339
-
项目类别:
-
资助金额:$12.05万
-
财政年份:2008
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负责人:Andrew P Rice
-
依托单位:
Targeting the PDZ-ligand domain of avian> influenza A viruses for novel therapeut
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批准号:7649153
-
项目类别:
-
资助金额:$20.2万
-
财政年份:2008
-
负责人:Andrew P Rice
-
依托单位:
海外基金