课题基金 / 基金详情

INDENTIFCATION OF PROTEIN THAT INTERACT WITH DHDAC4

INDENTIFCATION OF PROTEIN THAT INTERACT WITH DHDAC4
与 DHDAC4 相互作用的蛋白质的鉴定
批准号：
8171442
负责人：
MARC R MONTMINY
金额：
$0.24万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
2010
资助国家：
美国
项目状态：
已结题
起止时间：
2010-09-01 至 2011-08-31
来源：
https://reporter.nih.gov/project-details/8171442
关键词：
Computer Retrieval of Information on Scientific Projects DatabaseDrosophila genusFundingGene ExpressionGrantHDAC4 geneInstitutionMetabolicMuscle functionProteinsResearchResearch PersonnelResourcesRoleSignal TransductionSourceTissuesUnited States National Institutes of Healthnovel

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中文摘要
翻译
这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 IIa类HDAC优先在肌肉中表达，在肌肉中它们充当基因表达的信号依赖性阻遏物。为了了解HDAC 4在果蝇代谢组织中的作用，我们的目的是鉴定果蝇中HDAC 4的新相互作用蛋白。
英文摘要
This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Class IIa HDACs are preferentially expressed in muscles, where they function as a signal-dependent repressors of gene expression. To understand their role in metabolic tissues in Drosophila, we aimed to identify novel interaction proteins of HDAC4 in Drosophila.
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