MOLECULAR FUNCTION OF XCT, A CONSERVED CLOCK-ASSOCIATED GENE

这个子项目是许多利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 我们已经克隆了一个新的基因XCT，它对生物钟功能和光信号传导都很重要 在植物中。 XCT在真核生物中是高度保守的，是发育所必需的。 后生动物，但在任何生物体中没有已知的分子功能。 我们将使用基因和 在裂变酵母和植物中的生物化学技术，以确定作用的分子模式 的XCT。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. We have cloned a novel gene, XCT, which is important for clock function and light signaling in plants. XCT is highly conserved across eukaryotes, is essential for development in metazoa, but has no known molecular function in any organism. We will use genetic and biochemical techniques in fission yeast and plants to determine the molecular mode of action of XCT.