Center for Education and Research on Mental Health Therapeutics

描述(由申请人提供)：罗格斯-哥伦比亚精神健康治疗教育和研究中心将专注于为行为健康障碍患者安全有效地使用治疗药物。中心项目和活动将解决重大差距 在证据的基础上对心理健康治疗和服务体系的有效性进行比较创新。我们将建立在基础设施、合作伙伴关系、数据集开发和我们作为CERTS研究中心工作的头五年的研究路线的坚实基础上，以解决所有五个方案感兴趣的领域。拟议的工作将由系统的利益相关者通过咨询委员会提供的意见指导，咨询委员会代表有能力将中心的调查结果转化为改进的护理过程和结果的组织。研究和教育活动将得到数据、方法和生物统计核心以及教育、翻译和利益攸关方核心的支持，并在1)青年、2)成年人和3)虚弱老年人的人口核心范围内组织。具体项目包括：1)治疗难治性精神分裂症替代药理策略的比较有效性分析；2)以全州社区精神卫生中心为基础的创新型疗养院模式对安全有效使用精神健康治疗药物的影响分析；3)疗养院老年人抗痴呆药物的比较安全性分析；4)结构化诊断访谈对患有严重精神障碍的青年的管理和预后的潜在影响的检查；5)精神分裂症患者过早死亡率及其一般医疗服务基本质量的评估。通过这些项目和相关的教育活动，该中心旨在成为一个值得信赖的国家资源，为心理健康利益攸关方的决策提供信息，重点是广大接受治疗的人群，特别是在医疗补助和医疗保险方面。我们与各州和联邦政策制定者合作的经验也使我们有资格领导涉及医疗补助机构和复杂、高成本患者的新的跨CERT倡议 公共卫生相关性：精神健康状况在总体疾病负担和医疗保健支出中占很大份额，并使其他医疗疾病的病程和治疗变得非常复杂。该中心的工作将解决这些关键问题，作为一个关于大型日常护理环境中精神卫生治疗的使用和结果的国家观察站，纳入与关键利益攸关方的强有力的伙伴关系。

DESCRIPTION (provided by applicant): The Rutgers-Columbia Center for Education and Research on Mental Health Therapeutics will focus on safe and effective use of therapeutics for persons with behavioral health disorders. Center projects and activities will address critical gaps in the evidence base on the comparative effectiveness of mental health treatments and services system innovations. We will build on the solid foundation of infrastructure, partnerships, dataset development, and lines of research from our first five years of work as a CERTs Research Center to address all five programmatic interest areas. The proposed work will be guided by systematic stakeholder input through an advisory committee representing organizations that are well positioned to translate Center findings into improved care processes and outcomes. Research and educational activities will be supported by a Data, Methods and Biostatistics Core and an Education, Translation and Stakeholder Core and organized within population-based cores for 1) youth, 2) adults, and 3) the frail elderly. Specific projects include: 1) a comparativ effectiveness analysis of alternative pharmacological strategies to manage treatment-resistant schizophrenia, 2) an analysis of the impact of an innovative statewide community mental health center-based medical home model for the safe and effective use of mental health therapeutics, 3) a comparative safety analysis of anti-dementia medications in the nursing home elderly, 4) an examination of the potential impact of structured diagnostic interviewing on the management and outcome of youth with severe psychiatric disorders, and 5) an assessment of premature mortality in schizophrenia patients and their underlying quality of general medical care. Through these projects and related educational activities, the Center aims to serve as a trusted national resource to inform decision's making of mental health stakeholders, with an emphasis on broad populations -under treatment, especially in Medicaid and Medicare. Our experience working with states and federal policy makers also qualifies us to provide leadership of new cross-CERTs initiatives involving Medicaid agencies and complex, high-cost patients PUBLIC HEALTH RELEVANCE: Mental health conditions account for a substantial share of overall illness burden and health care expenditure, and substantially complicate the course and treatment of other medical disorders. The Center's work will address these critical issues, serving as a national observatory on the use and outcomes of mental health treatments in large, usual-care settings, incorporating strong partnerships with key stakeholders.