MSU Clinical Center Animal Facility HVAC Upgrade

描述（由申请人提供）：项目摘要：密歇根州立大学（MSU）目前正在进行总体规划，以确保继续使用最先进的设施来饲养实验室动物进行研究和教学。一些实验室动物设施达到了需要升级的年龄，该机构将根据设施的使用、条件和长期可行性进行选择性投资，因此，并非所有设施都将继续投资，导致动物舍的停止使用。这项研究的初步结论是，我们的首要动物护理机构，临床中心动物机构（CCAF），将需要改造工程系统。CCAF是密歇根州立大学的主要实验动物设施，用于支持生物医学和行为研究的进行。在这些升级之后，该设施将支持超过46名教职员工的研究。MSU将以超过3：1的比例与NIH的资金相匹配。拟议工程计划的重点是提升中区填海空军基地的暖气、通风及空调系统。虽然已经有35年的历史，CCAF是一个设计非常精良的设施。该设施的布局是灵活的，以适应各种各样的研究，并可以横向或纵向扩展为未来的增长。在每层楼的上方都有一个全高的间隙空间，使这个暖通空调升级项目能够经济有效地进行。CCAF HVAC系统是原创的，其可靠的使用寿命即将结束。本次改造工程将更换现有的老化部件，并增加系统的冗余和中央报警。拟议的翻修将确保保持严格的环境控制，以实现最佳的动物健康和福利以及可靠的研究数据，方法是更换老化的暖通空调设备，并确保在新设备出现故障或在计划维修期间有冗余。一旦升级，该设施将在一些较小的校园动物设施的翻新和维护期间提供空间，为被认为不适合翻新的设施中的动物提供住房，并容纳再生医学，神经科学和传染病，疾病的分子机制，生物医学工程和胃肠病学/微生物生态学领域的新教师的研究。密歇根州立大学是一所公立、赠地机构，被卡内基基金会指定为研究型大学。密歇根州立大学是美国第一所教授科学农业的高等学府，提供由17所授予学位的学院提供的200多个研究项目，吸引了世界各地的学者。作为一所综合性研究型大学，密歇根州立大学拥有5,000名教职员工，6,300名支持人员，36,400多名本科生和近10,800名研究生和专业学生。2009- 2010年的总入学人数超过47，200人，使密歇根州立大学成为美国十大大学之一。

DESCRIPTION (provided by applicant): Project Summary: Michigan State University (MSU) is currently undertaking a master planning exercise to ensure that state-of- the-art facilities continue to be used to house laboratory animals for research and teaching. Several of the laboratory animal facilities are reaching the age where they will require upgrades and the institution will make selective investments based on the use, condition and long-term viability of the facility, thus not all facilities will continue to be invested in resulting in discontinued use for animal housing. An initial conclusion from this study is that our premier animal care facility, the Clinical Center Animal Facility (CCAF), will require renovation of the engineering systems. The CCAF is the major laboratory animal facility at MSU used to support the conduct of biomedical and behavioral research. Following these upgrades the facility will support the research of over 46 faculty members. MSU will match the NIH funding in excess of a 3:1 ratio. The proposed project focuses on upgrading the heating, ventilation and air-conditioning (HVAC) system of the CCAF. Although almost 35 years old, the CCAF is an extremely well-designed facility. The layout of the facility is flexible to accommodate a wide variety of research and can be expanded horizontally or vertically for future growth. There is a full height interstitial space above each of the floors allowing this HVAC upgrade project to be carried out cost effectively. The CCAF HVAC system is original and nearing the end of its reliable lifespan. This renovation project will replace the current aged components, and add redundancy and central alarming of the system. The proposed renovation will ensure that tight environmental controls are maintained for optimal animal health and welfare and reliable research data, by replacing the aging HVAC equipment and ensuring redundancy should the new equipment malfunction or during times of planned maintenance. Once upgraded, this facility will provide space during renovation and maintenance of some of the smaller campus animal facilities, housing for animals in facilities deemed not optimal to renovate, and to accommodate the research of new faculty in the areas of regenerative medicine, neuroscience, and infectious disease, molecular mechanisms of disease, biomedical engineering and gastroenterology /microbial ecology. MSU is a public, land-grant institution designated as a Research-Extensive university by the Carnegie Foundation. The first institution of higher learning in the United States to teach scientific agriculture, MSU offers more than 200 programs of study offered by 17 degree-granting colleges that attract scholars worldwide. As a comprehensive research university, MSU has 5,000 faculty and academic staff, 6,300 support staff, more than 36,400 undergraduate and nearly 10,800 graduate and professional students. Total enrollment for 2009- 2010 exceeded 47,200, making MSU one of the ten largest universities in the United States.