Multidisciplinary Studies of Hematopoietic Malignancies

1.我们完成了主要病例对照研究的分析，并在同行评议期刊上发表了约50篇报告。2.我们证明了不同的淋巴瘤亚型的风险模式是不同的。3.我们发现发生非霍奇金淋巴瘤的遗传危险因素也可以预测生存；我们正在继续探索其他亚型，以比较病因和生存模式。4.为了更好地进行遗传多样性分析和研究，我们在InterLymph内部进行了数据汇集。5.我们继续与InterLymph合作，并报告了超重、阳光、丙型肝炎病毒、染发剂和生殖史的综合估计。6.我们将其他来源的环境数据与研究数据结合起来，继续调查环境风险。这项工作正在进行中。

1. We completed analysis of the main case-control study and published approximately 50 reports in peer-reviewed journals. 2. We demonstrated that the patterns of risk vary according to the subtype of lymphoma. 3. We showed that genetic risk factors for occurrance of NHL also predicted survival; We're continuing to explore other subtypes to compare the patterns of etiology and survival. 4. To conduct a GWAS and to study the genetic polymorphism with more power, we are pooling data within Interlymph. 5. We continued to collaborate with InterLymph and we reported on the pooled estimates for overweight, sunlight, hepatitis C virus, hair dyes, and reproductive history. 6. We combined environmental data from other sources with study data to continue to investigate environmental risks. This work is ongoing.