Improved patient outcomes through dosage individualisation of the newer immunosuppressant drugs
Improved patient outcomes through dosage individualisation of the newer immunosuppressant drugs
批准号:
nhmrc : 511109
负责人:
Dr Christine Staatz
金额:
$32.42万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31
中文摘要
器官移植后,接受者需要持续服用药物来阻止免疫系统排斥新器官。这种免疫抑制药物治疗对移植的长期成功至关重要。然而,由于管理不善的免疫抑制,太多的人正在失去他们的移植,或者正在经历药物毒性或感染。该项目旨在准确确定在澳大利亚移植人群中使用新免疫抑制药物的最佳方式。
英文摘要
After organ transplantation, recipients need to take medicines continually to stop their immune system from rejecting their new organ. This treatment with immunosuppressant drugs is vital for long-term success of their graft. However, too many people are losing their transplant or are experiencing drug toxicity or infection due to poorly managed immunosuppression. The project aims to accurately define the best way to dose newer immunosuppressant drugs in Australian transplant populations.
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会议论文
Population pharmacokinetic and pharmacodynamic modelling of the newer immunosuppressant drugs
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批准号:nhmrc : 301259
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项目类别:Early Career Fellowships
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资助金额:$21.94万
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财政年份:2004
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负责人:Dr Christine Staatz
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依托单位:
海外基金