Cancer Risk and Disparities

项目总结(见说明)： 癌症风险和差异计划的使命是支持将导致降低全社会癌症风险和差异的研究。为实现这一目标，该方案有以下四个具体目标： 1.了解个人、心理社会、组织和社区层面的因素，这些因素决定了不同生命周期和人群的癌症风险差异。 2.制定、测试和评估干预措施，以降低整个生命周期和人群的癌症风险。 3.促进传播和知识转化的科学，促进循证干预措施的传播，以降低癌症风险。 4.审查癌症风险和发病率差异的原因，并确定纠正这些差异的干预措施。 该计划最初于2000年获得资助，当时达纳-法伯/哈佛癌症中心作为一个联合体中心成立，并在2005年最后一次续签时获得了“优秀到杰出”的优秀分数。该计划由L.Frazier(DFCI)领导。有两位联合领导者：K.Viswanath(DFCI)和D.Williams(HSPH)。在目前的项目期间，该计划的目标进行了重大修订，纳入了新的研究重点，包括：1)易患癌症风险的个人和社会因素，2)传播科学，3)明确关注癌症差异，所有这些都代表了该计划内扩大和充满活力的优势。49个成员的专业知识涵盖流行病学、分子流行病学、行为科学、传播科学、干预科学、卫生政策和传播。2009年，该项目获得了1970万美元的癌症相关资金(总成本)，其中包括超过1190万美元的NCI资金和650万美元的其他联邦同行审查资金。方案成员在项目期间(2006至2010年)撰写的903份出版物证明了方案的生产力和互动性，其中15.5%是方案内出版物，18%是方案间出版物，16%是方案间出版物 机构间合作。

PROJECT SUMMARY (See instructions): The mission of the Cancer Risk and Disparities Program is to support research that will lead to a reduction of cancer risk and disparities across society. To achieve this goal, the Program has the following four specific aims: 1. Understand the individual, psychosocial, organizational and community-level factors that determine differences in cancer risk across the life course and population groups. 2. Develop, test and evaluate interventions to reduce cancer risk across the life course and population groups. 3. Advance the science of communication and knowledge translation to promote dissemination of evidence-based interventions to reduce cancer risk. 4. Examine causes of disparities in cancer risk and incidence and Identify interventions to redress these disparities. The Program was initially funded in 2000 when the Dana-Farber/Harvard Cancer Center was established as a consortium Center, and received a merit score of "excellent to outstanding" at the time of the last renewal in 2005. The Program Is led by L. Frazier(DFCI). There are two Co-Leaders: K. Viswanath (DFCI) and D. Williams(HSPH). During the current project period, the goals of the Program were substantially revised to include new research foci including: 1) the individual and societal factors that predispose to cancer risk, 2) the science of dissemination and 3) an explicit focus on cancer disparities, all of which represent expanded and vibrant strengths within the Program. The expertise of the 49 members spans epidemiology, molecular epidemiology, behavioral science, communication science, intervention science, health policy and dissemination. In 2009, the Program received $19.7 million in cancer-relevant funding (total costs), which included over $11.9 million in NCI funding and $6.5 million in other federal, peer-reviewed funding. Attesting to the productivity and interactivity of the Program are the 903 publications authored by members of the Program during the project period (2006 to 2010), of which 15.5% were Intra-programmatic ,18% were inter-programmatic and 16% were inter-institutional collaborations.