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中文摘要
翻译
UWCCC建议为其成员提供特定协议研究支持, 临床/转化研究将受益于及时的资助。UWCCC历史悠久 资助试点研究,导致更及时的临床研究和NCI资助。UWCC已经 在上一个资助期内资助了15项(其中8项正在进行或最近启动)早期试点临床研究 累计173例受试者。UWCCC支持的研究的有效累积得到了加强, UWCCC支持的全州临床试验网络(威斯康星州肿瘤学网络)。这种支持方式 允许有新想法或有希望的初步试验数据的研究人员申请支持研究 护士和数据管理员进行高优先级,创新,可行性和早期机构临床 研究协议。每年将征求两次提案,并将进行同行审查(根据 副董事H。Bailey和P. Sondel),根据科学价值进行选择,需要 方案特定的研究资金,可能导致NCI资金,和UWCCC研究优先事项。一旦 选定的方案从该机制获得研究护士/数据管理支持, 通过Oncore数据库提供必要的开发和监管支持,以进行UWCCC要求的监测 和报告。
英文摘要
The UWCCC proposes to have available for its members Protocol Specific Research support for pilot clinical/translational research studies that would benefit from timely funding. The UWCCC has a long history of funding pilot studies that have led to more timely clinical research and NCI funding. The UWCCC has funded 15 (8 of these ongoing or recently initiated) early phase pilot clinical studies over the last grant period with an accrual of 173 subjects. Efficient accrual to UWCCC-supported studies is enhanced by the UWCCC-supported statewide clinical trials network (Wisconsin Oncology Network). This method of support allows investigators with emerging ideas or promising initial pilot data to apply for the support of a research nurse and data manager to conduct high priority, innovative, feasibility and early stage institutional clinical research protocols. Proposals will be requested twice yearly and will undergo peer-review (under the direction of Associate Directors H. Bailey and P. Sondel) with selection based on scientific merit, need for Protocol Specific Research funding, potential to lead to NCI funding, and UWCCC research priorities. Once selected, protocols receive research nurse/data management support from this mechanism and all the necessary developmental and regulatory support via the Oncore database for UWCCC-required monitoring and reporting.
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Stress keratin 17 and CD4/8 ratio as prognostic markers in HIV-related anogenital squamous cell precancers and cancers (Biospecimens/Biocohort)
  • 批准号:
    10620051
  • 项目类别:
  • 资助金额:
    $23.9万
  • 财政年份:
    2022
  • 负责人:
    HOWARD H. BAILEY
  • 依托单位:
Defining Tumor Microenvironment and Response to Immune Checkpoint Blockade in HIV-related Anogenital Squamous Cell Carcinomas (Immuno/microenvironment)
  • 批准号:
    10620043
  • 项目类别:
  • 资助金额:
    $24.47万
  • 财政年份:
    2022
  • 负责人:
    HOWARD H. BAILEY
  • 依托单位:
Creating An Efficient Clinical Trial Build System via The Clinical Trials Rapid Activation Consortium (CTRAC)
  • 批准号:
    10227524
  • 项目类别:
  • 资助金额:
    $30.02万
  • 财政年份:
    2020
  • 负责人:
    HOWARD H. BAILEY
  • 依托单位:
The MW Cancer Prevention Clinical Trials Network
  • 批准号:
    10252839
  • 项目类别:
  • 资助金额:
    $171.64万
  • 财政年份:
    2020
  • 负责人:
    HOWARD H. BAILEY
  • 依托单位:
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