Women's Cancers

妇女癌症方案领域由19名成员组成，跨越加州大学洛杉矶分校的7个部门。在 在过去的竞争周期中，该计划的研究人员撰写了199篇出版物，其中39篇（20%）是 方案间和27个（14%）方案内。60篇（30%）发表在高影响力期刊上。10 该计划领域的成员使用了目前由JCCC资助的8种共享资源中的5种。 在本资助年度，同行评审的资金总额为1220万美元，其中包括240万美元。 国家癌症研究所的百万美元。与其他计划领域一样，JCCC促进了一些互动的 活动和许多支持妇女癌症项目研究人员的共享资源 区在目前的赠款周期内，来自JCCC的资金以CCSG发展基金的形式， 对GR计划区的机构支持和慈善捐赠总额为991，008美元。这些资金支持 跨学科赠款、种子赠款、招聘/留用、计划领域领导支持、 利用新兴的共享资源和学员。九个项目区成员获得了 JCCC支持。 妇女癌症计划旨在解决研究，临床和教育活动， 女性的恶性肿瘤该计划促进了相互之间的互动和合作活动， 为了在乳房和妇女生殖领域开展多学科研究， 癌的它采用综合方法进行临床癌症研究，重点是转化研究。 妇女癌症计划的目标是：1）建立基于遗传学的风险评估和咨询 通过了解高风险/遗传易感性; 2）评估和实施预防和筛查 通过了解高风险/遗传易感性的策略; 4）调查分子/遗传和 环境条件，导致妇女癌症的可能早期干预， 早期细胞转化事件; 5）通过了解 实体瘤进展/血管生成/侵袭的机制;和6）鉴定靶标并开发新的， 合理、高效、低毒的治疗方法， 肿瘤/运动性/转移。

The Women's Cancers Program Area is composed of 19 members, spanning 7 Departments within UCLA. In the past competing cycle, investigators from this Program authored 199 publications, of which 39 (20%) were inter-programmatic and 27 (14%) intra-programmatic. 60 (30%) were placed in high-impact journals. 10 members of this Program Area used 5 out of the 8 Shared Resources that are currently funded by the JCCC. During the current funding year, peer-reviewed funding totaled $12.2 million in total costs, including $2.4 million from the National Cancer Institute. As with other Program Areas, JCCC fosters a number of interactive activities and many of the Shared Resources that support investigators in the Women's Cancers Program Area. During the current grant cycle, funds from the JCCC in the form of CCSG Developmental Funds, institutional support and philanthropic gifts to the GR Program Area total $991,008. These funds supported Interdisciplinary Grants, Seed Grants, recruitment/retention, Program Area Leadership support, funding for the use of emerging Shared Resources and trainees. Nine of the Program Area Members were the recipients of JCCC support. The Women's Cancers Program seeks to address research, clinical, and educational activities for malignancies in women. The Program fosters interactive and collaborative activities between and among members in order to develop multidisciplinary research in the areas of breast and women's reproductive cancers. It takes a comprehensive approach to clinical cancer research with a focus on translational research. The goals of the Women's Cancers Program are: 1) Establish genetic-based risk assessment and counseling by understanding high-risk/genetic predisposition; 2) Evaluate and implement prevention and screening strategies by understanding high-risk/genetic predisposition; 4) Investigate the molecular/genetic and environmental conditions that give rise to cancers in women for possible early intervention by understanding early cellular transformation events; 5) Develop targeted therapeutics for women's cancers by understanding the mechanisms of solid tumor progression/angiogenesis/invasion; and 6) Identify targets and develop new, rational, highly effective and minimally toxic therapeutic approaches by understanding established tumors/motility/metastasis.