BEHAVIORAL TESTING

行为测试核心位于BBSRB地下室的两个房间内。B028是用于大鼠行为评估的专用房间，其中核心具有进行以下测试的能力：a）使用Morris水迷宫系统的学习和记忆的认知测试，B）使用胡须滋扰任务的感觉测试，c）使用Hargreaves足底装置的伤害感受测试，和d）使用Basso，Beattie，Bresnahan（BBB）量表和足部错位仪（水平梯）。 B030是用于小鼠行为评估的专用房间，其中Core具有使用白色Morris水迷宫（用于黑色小鼠）或黑色迷宫（用于白色小鼠）结合更新的数字跟踪系统进行学习和记忆的认知测试的能力。还可以使用转角测试评估小鼠的感觉运动功能，使用旋转棒装置评估前庭能力，以及使用复合神经评分、神经严重性评分和复杂运动功能来评估小鼠的感觉运动功能。 得分Basso小鼠量表（BMS）、握力计和绳测试。用P30资金购买的具体仪器包括2台AccuScan仪器EzVideoDV自动跟踪系统数字系统、一台哥伦布仪器Rotamex-5和足部错位仪、2台镇痛仪和一个用于开阔场地运动评估的浅水池。Kathryn Saatman博士指导行为测试核心 沿着的还有助理核心主管亚历山大·拉切夫斯基。Stephen Onifer博士提供核心运营的日常管理，并监督培训，数据存储和传播以及核心使用。 两名受过啮齿动物TBI模型（Jennifer Pleasant女士，25%努力）和SCI模型（Travis Lyttle先生，25%努力）行为测试培训的高级技术人员协助并指导新核心用户进行行为评估。

The Behavioral Testing Core is housed within two rooms in the basement of BBSRB. B028 is a dedicated room for behavioral assessment of rats, in which the Core has the capability of performing a) cognitive testing of learning and memory using a Morris water maze system, b) sensory testing using a whisker nuisance task, c) nociceptive testing using a Hargreaves plantar device, and d) locomotor function testing using the Basso, Beattie, Bresnahan (BBB) scale and the foot misplacement apparatus (horizontal ladder). B030 is a dedicated room for behavioral assessment of mice, in which the Core has the capability of performing cognitive testing of learning and memory using a white Morris water maze (for black mice) or a black maze (for white mice) in conjunction with an updated digital tracking system. Mice can also be evaluated for sensorimotor function using a corner turn test, vestibulomotor ability using the rotarod apparatus, and simple and complex motor function using the composite neuroscore, neurological severity score. Basso mouse scale (BMS), grip strength meter, and string test. Specific instruments purchased with P30 funds include 2 AccuScan Instruments EzVideoDV Automated Tracking System Digital Systems, a Columbus Instruments Rotamex-5 and Foot Misplacement Apparatus, 2 analgesia meters and a wading pool for open field locomotor assessment. Kathryn Saatman, Ph.D. directs the Behavioral Testing Core along with Assistant Core Director, Alexander Rabchevsky. Stephen Onifer, Ph.D provide day-to-day management of core operations and overseeing training, data storage and dissemination, and core usage. Two senior technicians who are trained in behavioral testing in rodent TBI models (Ms. Jennifer Pleasant, 25% effort) and SCI models (Mr. Travis Lyttle, 25% effort) assist and instruct new core users with the behavioral assessments.