Pediatric Rheumatology Research Annual Scientific Meeting

描述（由申请人提供）：儿科风湿病研究年度科学会议将是儿科风湿病学界分享最先进的科学方法，科学机会和新技术的论坛。该提案是我们之前的会议拨款的延续，用于支持2012年、2013年、2014年、2015年和2016年的会议。这些会议将由儿童关节炎和风湿病研究联盟（CARRA）共同主办，这是一个由美国和加拿大大多数儿科风湿病学家组成的研究网络。这些会议预计为期两天半，将邀请CARRA的所有成员、儿科风湿病学界、对儿科风湿病研究感兴趣的个人以及相关领域（内科风湿病学、免疫学、流行病学和其他儿科研究网络）的特邀演讲者和专家参加。在2012年、2014年和2016年的会议上，为期一天的名为“临床研究要点”的研讨会将在为期两天半的科学年会之前举行。为期一天的研讨会将提供教学和互动课程，内容涉及治疗医生和PI之间的紧张关系、IRB的角色、同意书和同意流程、不良事件报告、优化研究启动、招募和保留、研究监测、现场责任、试验药物处理、方案审查以及现场预算和合同。2013年和2015年的会议将是为期两天半的科学会议，有更多的时间在每个主要疾病领域制定方案。所有会议将包括与儿科风湿病和临床研究方法相关的转化主题的教学会议，以及制定方案的时间。便利的互动式会议将确定每个主要疾病领域的主要研究需要和机会，并将未来发展的科学优先事项发展为具体的研究项目。将确定和培养合作机会和指导关系，并确定与临床研究问题协调的转化研究机会。本次会议的目标是：1。提高我们对儿童风湿病发病机制（免疫、遗传、表观遗传和炎症）、流行病学以及当前和创新治疗方法的理解；2. 为儿科风湿病研究界提供合作发展和指导论坛，特别关注年轻研究人员；3. 提供与临床儿科风湿病学研究和临床研究相关的主要领域的培训和教育。4. 将儿科风湿病研究协调员整合到CARRA研究战略的推进和具体研究项目的发展中，本次会议将是CARRA实现其主要使命的主要途径之一，该使命是促进高质量研究的发展，并最终创建一个包括每种儿科风湿病相关研究项目的研究组合。

DESCRIPTION (provided by applicant): The Pediatric Rheumatology Research Annual Scientific Meeting will be the forum for the pediatric rheumatology community for sharing the scientific state-of-the-art methodologies, scientific opportunities and new technologies. This proposal is a renewal of our previous conference grant to support meetings in 2012, 2013, 2014, 2015 and 2016. These meeting will be co-sponsored by the Childhood Arthritis and Rheumatology Research Alliance (CARRA), a research network comprising the majority of pediatric rheumatologists in the US and Canada. These meetings are conceived to be 2 1/2 days and all members of CARRA, the pediatric rheumatology community, individuals interested in pediatric rheumatic disease research will be invited to attend as well as invited speakers and experts in related fields (internal medicine rheumatology, immunology, epidemiology, and other pediatric research networks). In 2012, 2014 and 2016 meeting a one day workshop called 'Essentials of Clinical Research' will be held preceding the 2 & 1/2 day scientific annual meeting.. The one day workshop will offer a mix of didactic and interactive sessions on the tension between being a treating physician and PI, role of the IRB, consent forms and consenting process, adverse event reporting, optimizing study start up, recruitment and retention, monitoring of studies, site responsibilities, investigational drug handling, protocol review, and site budgeting and contracts. The 2013 and 2015 meetings will be 2 & 1/2 day scientific meetings with more time for protocol development in each major disease area. All meetings will have a mix of didactic sessions on translational topics relevant to pediatric rheumatologic diseases and clinical research methodology, and time for development of protocols. Facilitated interactive sessions will identify the key research needs and opportunities in each of the major disease area, with development of the scientific priorities for future development into specific research projects. Collaborative opportunities and mentoring relationships will be identified and fostered, and translational research opportunities will be identified in coordination with clinical research questions. The objectives of this meeting are to: 1. To advance our understanding of the pathogenesis (immune, genetic, epigenetic and inflammatory), epidemiology, and current and innovative therapeutic approaches in pediatric rheumatic diseases; 2. Provide a forum for development of collaborations and mentoring for the pediatric rheumatology research community with special attention to young investigators; 3. Provide training and education in major areas relevant to clinical pediatric rheumatology research and the conduct of clinical research. 4. To integrate pediatric rheumatology research coordinators into the advancement of the CARRA research strategy and the development of specific research projects This meeting will be one of the major avenues whereby CARRA will achieve its primary mission of facilitating the development of high-quality research studies and ultimately creating a research portfolio that includes relevant research projects in every type of pediatric rheumatic disease.