UIC CENTERS FOR POPULATION HEALTH AND HEALTH DISPARITIES

描述（由申请人提供）：本提案旨在更新UlC人口健康和健康差异中心（P50 CA 10674）。该中心是五个全部或部分由国家癌症研究所资助的中心之一，作为NIH最初倡议的一部分。这是一个多个主要研究者的应用程序。中心主题是：了解我们以前的研究如何确定与种族/民族有关的乳腺癌诊断阶段差异的根本原因，从而导致基于该研究的干预措施？该中心拟议更新的当前目标是解决三个问题，这些问题是根据我们迄今为止的工作，在理解白色妇女和有色人种妇女之间乳腺癌诊断阶段的差异方面出现的核心问题。（一）确定如何解决安全网医院在早期发现、诊断和治疗方面的明显差距？2a）确定社区卫生诊所如何更有效地识别和监测有侵袭性乳腺癌风险的患者。2b）确定如何让高风险患者参与定制的筛查和监测计划。3)为了确定生物因素，特别是DNA甲基化，如何促进有色人种女性中侵袭性乳腺癌的不成比例？.有三个项目：1）医疗服务不足地区的患者导航。（E.卡尔霍恩，PI）2）乳腺癌筛查干预，以提高对癌症控制指南在服务不足的少数民族妇女（K。霍斯金斯，PI）; DNA甲基化和不同种族/种族的癌症侵袭性（G. Rauscher，PI）和四个核心：行政（R. Warnecke（Contact）& E.卡尔霍恩（联合核心领导人）;政策和传播（C。Ferrans，CL）;数据管理和评价（T.约翰逊，（CL）和培训和职业发展（F戴维斯，CL）我们的持续，长期的愿景是测试和建立干预措施，解决人口健康差异的决定因素，接近他们与多层次和多学科的人口健康战略。为此，我们将：1）开展研究，影响有关获得乳房X光检查和乳腺癌管理的政策，并确保平等获得标准的乳腺癌护理，无论在哪里提供，也无论谁提出要求。2）使贫穷和服务不足的妇女认识到需要以确保最佳结果的方式获得护理。3)培养年轻学者在健康差距研究纳入跨学科的研究视角。

DESCRIPTION (provided by applicant): This proposal is for renewal of the UlC-Center for Population Health and Health Disparities (P50 CA10674). This Center is one of five that were funded in whole or in part by the National Cancer Institute as part of the initial NIH initiative. It is a Multiple Principal Investigator application. The center theme is: Understanding how our previous research identifying fundamental causes of disparities in stage at breast cancer diagnosis related to race/ethnicity can lead to interventions grounded in that research? The current aims of the proposed renewal of the Center are to address three questions that have emerged as central issues in understanding the disparity in stage at breast cancer diagnosis between White women and women of color based on our work to date. These are: I) To define how apparent disparities in early detection, diagnosis and treatment can be addressed in safety-net hospitals? 2a) Determine how community health clinics can more effectively identify and monitor patients at risk for aggressive breast cancer. 2b) Determine how patients at elevated risk can be engaged to participate in a tailored screening and monitoring program. 3) To determine how biological factors, specifically DNA methylation, promote aggressive breast cancer disproportionately among women of color? . There are three projects: .1) Patient Navigation in Medically Underserved Areas. (E. Calhoun, PI) 2) A Breast Cancer Screening Intervention to Improve Adherence to Cancer Control Guidelines in Underserved Minority Women (K. Hoskins, PI); DNA Methylation and Differential Cancer Aggressiveness by Race/Ethnicity (G. Rauscher, PI) and four cores: Administration (R. Warnecke (Contact) & E. Calhoun (Co- Core leaders); Policy and Dissemination (C. Ferrans, CL); Data Management and Evaluation (T. Johnson, (CL) and Training and Career Development (F Davis, CL ) Our continuing, long range vision is to test and establish interventions that address determinants of population health disparities by approaching them with a multilevel and multidisciplinary population health strategy. To accomplish this we will: 1) conduct research that impacts the policies that govern access to mammography and management of breast cancer and ensures equal access to the standard of breast cancer care regardless of where it is delivered and who requests it. 2) Enable women who are poor and underserved to recognize the need to access the care in ways that ensure the best outcomes. 3) To train young scholars in health disparities research incorporating a transdisciplinary research perspective.