IDENTIFICATION, SURVEILLANCE AND CONTROL OF VECTOR - BORNE AND ZOONOTIC INFECTIOU

描述（由申请人提供）：乌干达与撒哈拉以南非洲的许多国家一样，正处于公共卫生危机之中。在乌干达肆虐的大量传染病、病媒传播疾病和人畜共患疾病，造成了社会和经济发展的迟缓，并给人类带来了许多痛苦。在这项提案中，乌干达病毒研究所介绍了一个在乌干达调查和控制病媒传播和人畜共患疾病的多年项目。为了实现这一长期目标，本研究计划将侧重于评估乌干达由病媒传播和人畜共患疾病引起的疾病负担，描述乌干达与病媒传播和人畜共患疾病相关的地方病和兽疫参数，制定方案和技术以降低乌干达因病媒传播和人畜共患疾病引起的发病率和死亡率，描述乌干达病媒传播和人畜共患疾病的宿主和病媒特征。获得来自乌干达的细菌和病毒分离物的各种档案收集，最后，在实地条件下制定和评估经济上可持续的控制战略。

DESCRIPTION (provided by applicant): Uganda, like much of sub-Saharan Africa, is in the midst of a public health crisis. The great number of infectious, vector-borne and zoonotic diseases rampant in Uganda has caused a retardation of social and economic development and much human suffering. In this proposal, the Ugandan Virus Research Institute describes a multi-year project investigating and controlling vector-borne and zoonotic disease in Uganda. In order to achieve this long-term aim, this research proposal will focus on assessing the disease burden caused by vector-borne and zoonotic diseases in Uganda, describing the enzootic and epizootic parameters associated with vector-borne and zoonotic diseases in Uganda, developing programs and technology to reduce morbidity and mortality due to vector-borne and zoonotic diseases in Uganda, characterize the reservoir hosts and vectors of vector-borne and zoonotic diseases in Uganda, acquiring a diverse archive collection of bacterial and viral isolates from Uganda and lastly, developing and evaluating economically sustainable control strategies under field conditions.