RESEARCH CAREER DEVELOPMENT CORE

项目摘要 研究职业和发展核心（RCDC）促进独立调查人员在跨学科研究有关美国老年人的独立性老龄化的发展。这一核心强调以能力为基础的研究和领导技能的发展，将基本发现转化为临床研究和临床发现转化为基础研究。这种方法的关键是我们与我们大学的NIH临床和转化科学研究所（CTSI）和退伍军人事务老年医学研究教育和临床中心（GRECC）的合作伙伴关系。该核心资源与其他内部和外部资源相结合，以提供职业支持，例如NIH职业发展。少数民族补充，研究奖，奖学金，非NIH职业和研究奖，VA和CTSI支持。RCDC支持初级学者的研究培训，他们的范围从尚未资助的初级学员到高级学员。 已经成功竞争职业发展或提供大量工资支持的赠款的受训人员。初级学者从RCDC获得直接的工资支持，以保护他们的职业发展和研究的时间在他们发展的关键时期。高级初级学者可能已经有足够的工资支持，但有资格获得RCDC的指导，工作人员，基础设施和旅行资源，以及RCDC的培训活动。在我们的第一年，我们提出了6个初级学者，其中几个人有来自主要合作伙伴，他们的家庭部门，或早期职业生涯的资金共同资助。 RCDC的总体目标是满足所有OAlCs的目标，招募，选择和培养有才华的青年学者，他们致力于转化科学，并将老年人的健康/疾病和独立/残疾的临床见解与基础科学的进步知识相结合，以改善临床干预措施，保持健康和独立。为了实现这一目标，重点放在跨学科的职业发展计划，从不同的科学家干部（基础，翻译，社会，行为，流行病学和临床）产生综合知识。这需要利用其他OAIC核心设施：试点和探索性研究核心（PESC），临床研究核心（RCI），代谢和生物标志物核心（RC 2），生物统计和数据管理核心（RC 3）以及招募，依从性和保留核心（RC 4）。 详细的职业发展计划是为每个建议的初级学者由这个核心支持量身定制的。 此类计划包括但不限于：a）与本OAIC主题（肌肉减少症和残疾预防）相结合的研究项目，B）强调基础和临床研究整合以及OAIC研究范围内定期整合的正式培训策略，c）使用团队方法促进基础和临床科学方法的正式导师计划，以及d）监测进程，利用具体的成就里程碑正式评估受训人员的进展。

PROJECT SUMMARY The Research Career and Development Core (RCDC) promotes the development of independent investigators in interdisciplinary research on aging relevant to the independence of older Americans. This core emphasizes the competency-based development of research and leadership skills for translating basic findings into clinical research and clinical findings into basic research. Key to this approach is our partnerships with our university's NIH Clinical and Translational Science Institute (CTSI) and Veteran Affairs Geriatric Research Education and Clinical Center (GRECC). Resources of this core are integrated with other internal and external sources for career support, such as NIH career development. Minority Supplement, and research awards, fellowships, non-NIH career and research awards, VA, and CTSI support. The RCDC supports the research training of Junior Scholars who span the spectrum from beginning trainees not yet funded, to advanced trainees who already have competed successfully for career development or grants that provide substantial salary support. Beginning Junior Scholars receive direct salary support from the RCDC to protect their time for career development and research during the crucial period of their development. Advanced Junior Scholars may already have sufficient salary support, but are eligible for RCDC mentorship, and staff, infrastructure and travel resources, and RCDC training activities. In our first year, we propose 6 Junior Scholars, several of whom have co-funding from key partners, their home departments, or early career funding. The overarching goal of the RCDC is to meet the objective of all OAlCs to recruit, select, and train talented Junior Scholars who are committed to translational science and to integrating clinical insights of health / disease and independence / disability in older adults with knowledge of the advances in the basic sciences to improve clinical interventions for maintaining health and independence. To achieve this goal, emphasis is placed on an interdisciplinary career development plan that generates combined knowledge from a diverse cadre of scientists (basic, translational, social, behavioral, epidemiological, and clinical). This entails utilization of the other OAIC core facilities: the Pilots & Exploratory Studies Core (PESC), Clinical Research Core (RCI), Metabolism & Biomarkers Core (RC2), Biostatistics & Data Management Core (RC3), and the Recruitment, Adherence, & Retention Core (RC4). Detailed career development plans are tailored for each proposed Junior Scholar supported by this core. Such plans include, but are not limited to, a) a research project integrated with the theme of this OAIC, which is sarcopenia and prevention of disability, b) a formal training strategy that stresses the integration of basic and clinical research and regular integration across the OAIC spectrum of research, c) a formal mentorship program that uses a team approach to foster basic and clinical science approaches, and d) a monitoring process to formally evaluate the progress of trainees using specific milestones of achievements.