Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging Among Mid-Life Adults

引导情景未来思维，提高中年成年人体育活动的坚持并促进健康的大脑老化

• 批准号: 10897376
• 负责人: Laura E Martin
• 金额: $ 71.88万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-15 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10897376
• 关键词: Guided; Episodic; Future; Thinking; Increase

PROJECT SUMMARY/ABSTRACT Novel intervention strategies to increase physical activity need to reduce barriers to exercise and increase adherence to achieve optimal brain health benefits. Despite considerable physical and brain health benefits associated with exercise, most adults fail to adhere to recommended physical activity guidelines. Barriers, including lack of time and low enjoyment of exercise, can lead to reduced adherence. Dual-system neural models of behavior theorize two systems that drive behavior and can be engaged in interventions. The reward brain system responds to and evaluates the rewarding properties of stimuli in the environment and drives behaviors. The regulation brain system downregulates responses to rewarding stimuli and promotes healthy behaviors by helping individuals adhere to and achieve their goals. Our long-term goal is to develop enhancements to health behavior interventions that engage the reward and regulation mechanisms related to increase adherence and promote optimal brain health. The rationale for the proposed study is based on previous studies showing relationships between regulation, positive affect, and exercise and our preliminary data that show targeting the regulation and reward systems increases healthy choices and positive affect. we will apply the NIH Stage Model to develop guided imagery to target reward AND regulation brain systems and assess the impact on exercise adherence. First, we will test a brief guided imagery approach to engage regulation and reward brain systems and the acceptability of HIIT in mid-life adults (R61). We will use guided imagery that includes PAI to increase positive associations with exercise and/or EFT to increase focus on one's healthy, physically active, future self and increase regulation. We will dynamically refine the HIIT exercise intervention to increase acceptability. Systematically testing the independent effects of engaging reward or regulation on changes in reward and regulation indices and refining the HIIT protocol will help us develop the optimal behavioral and exercise intervention approach. Next, we will test this approach and the impact on exercise adherence and physical activity in a 6-week HIIT exercise intervention (R33). This innovative study fills a gap in the current literature by examining the impact of EFT and positive affect guided imagery among mid-life adults and will inform future interventions to improve health decision-making, promote healthy behaviors and brain health, and reduce the risk of developing Alzheimer's disease.

项目总结/摘要 增加身体活动的新干预策略需要减少运动障碍， 坚持以实现最佳的大脑健康益处。尽管对身体和大脑健康有相当大的好处 与锻炼有关，大多数成年人未能遵守推荐的身体活动指南。障碍， 包括缺乏时间和缺乏锻炼的乐趣，可导致坚持性降低。双系统神经网络 行为模型将两个驱动行为并可参与干预的系统理论化。奖励 大脑系统对环境和驱动器中刺激的奖励特性做出反应和评估 行为。大脑调节系统下调对奖励刺激的反应， 帮助个人坚持并实现他们的目标。我们的长期目标是发展 加强健康行为干预措施，涉及与以下方面有关的奖励和调节机制： 增加坚持和促进最佳大脑健康。拟议研究的理由是基于以前的 研究表明，调节，积极的影响和运动之间的关系，我们的初步数据， 显示针对监管和奖励系统增加健康的选择和积极的影响。我们将应用 美国国立卫生研究院阶段模型，以开发引导图像，以靶向奖励和调节大脑系统，并评估 影响锻炼坚持性。首先，我们将测试一种简短的引导图像方法，以参与监管， 奖励大脑系统和HIIT在中年人中的可接受性（R61）。我们将使用引导图像， 包括派以增加与锻炼的积极关联和/或EFT以增加对个人健康的关注， 身体活动，未来自我和增加调节。我们将动态地完善HIIT运动干预， 提高可接受性。系统地测试参与奖励或监管对 奖励和监管指数的变化以及改进HIIT协议将有助于我们制定最佳的 行为和运动干预方法。接下来，我们将测试这种方法以及对运动的影响 在为期6周的HIIT运动干预（R33）中的依从性和身体活动。这项创新研究填补了 通过研究中年人中EFT和积极情感引导意象的影响， 并将为未来的干预措施提供信息，以改善健康决策，促进健康行为和大脑 健康，并降低患阿尔茨海默病的风险。