Web-based Smoking Cessation Intervention: transition from inpatient to outpatient

描述（由申请人提供）：本项目旨在利用当前RCT（母研究）的基础设施，检查基于网络的戒烟干预的有效性和成本效益，使住院吸烟者在家中继续戒烟。在本研究和母研究中，共享招募和数据收集人员以及类似的方案，可以最大限度地提高收集流行病学和解释性数据的效率，以应对新出现的烟草趋势。电子烟的使用正在增加，特别是在试图戒烟的吸烟者中，而科学家们正在争论它们的潜在益处和危害。关于电子烟的使用及其使用中涉及的因果机制的知识有限。主要的具体目标是测试一个纵向中介模型，阐明电子烟使用中涉及的机制。具体来说，我们将确定谁使用以及为什么他们可能使用电子烟。这将包括对电子烟营销敏感性的预测因素 充分和传播第二个具体目标是收集有关吸烟者住院前后电子烟使用率的重要数据，为表征电子烟使用范围的流行病学知识库做出贡献。这项纵向观察性研究将招募980名年龄在19岁至80岁之间的吸烟者。根据我们目前的研究结果，我们预计32%是少数民族，48%是女性，28%已经尝试过电子烟。参与者将在基线时在医院床边接受采访，并在6个月和12个月后通过电话接受假设预测电子烟用途：的因素的采访：受电子烟预期影响的意图（和标准香烟），这是由对电子烟营销信息的敏感性驱动的，而电子烟营销信息又受到九个因素的影响。（电子烟暴露、烟草依赖、戒烟相关预期、健康素养、人口统计学、戒烟自我效能、戒烟动机、认知需求和个人参与）。这项研究的结果将促进对哪些吸烟者以及为什么这些吸烟者在一个丰富的样本中使用电子烟的理解（在住院时接受过戒烟建议和信息的吸烟者）。这也将包括电子烟营销活动的贡献，并代表着理解电子烟的看法及其在电子烟中的作用的关键第一步。 目前吸烟者的健康。需要推进这一理解，以指导FDA适当实施《家庭吸烟预防和烟草控制法》。 公共卫生相关性：该提案旨在促进对住院吸烟者使用电子烟的机制的理解（即，谁使用电子烟，以及哪些因素解释了这些人为什么使用它们）。与此RFA一致，电子烟营销活动的贡献将被纳入新颖的概念模型中 通过成瘾，健康行为和营销/传播理论，将通过纵向中介分析进行检查。因此，目前的提案是朝着最大限度地减少电子烟对公众健康构成的威胁迈出的关键的第一步

DESCRIPTION (provided by applicant): This project is designed to take advantage of the infrastructure in place for a current RCT (parent study) examining the effectiveness and cost-effectiveness of a web-based smoking cessation intervention that transitions hospitalized smokers to continue abstinence at home. Sharing recruitment and data collection staff and similar protocols across this and the parent study maximizes efficiency to collect epidemiologic and explanatory data for an emerging tobacco trend. Electronic-cigarette use is increasing, particularly among smokers trying to quit, while scientists debate their potential for benefit and harm. There is limited knowledge about e- cigarette use and the causal mechanisms involved in their use. The Primary specific aim is to test a longitudinal mediation model elucidating mechanisms involved in e-cigarette use. Specifically, we will identify who uses and why they are likely to use e-cigarettes. This will include predictors of susceptibility to e-cigarette marketing messages. The Secondary specific aim is to collect important data regarding the prevalence of e-cigarette use among smokers both before and after their hospitalization, contributing to the epidemiologic knowledge base characterizing the scope of e-cigarette use. This longitudinal observational study will recruit 980 cigarette smokers between the ages of 19 and 80 during hospitalization. Based on findings from our current study, we expected 32% to be minority, 48% female and 28% to have already tried e-cigarettes. Participants will be interviewed at hospital bedside at baseline and via telephone 6 and 12 months later on factors hypothesized to predict e-cigarette use: intention which is influenced by expectancies for e-cigarettes (and standard cigarettes) which are driven by susceptibility to e- cigarette marketing messages which in turn is influenced by nine factors (e-cigarette exposure, tobacco dependence, abstinence related expectancies, health literacy, demographics, abstinence self-efficacy, motivation to quit, need for cognition and personal involvement). Findings from this research will advance the understanding of which smokers and why these smokers use e- cigarettes among an enriched sample (smokers who have received smoking cessation advice and information when hospitalized). This will also include the contribution of e-cigarette marketing activities and represents a critical first step toward understanding perceptions of e-cigarettes and their role in the health of current smokers. Advancing this understanding is needed to guide the FDA to appropriately implement the Family Smoking Prevention and Tobacco Control Act. PUBLIC HEALTH RELEVANCE: This proposal aims to advance the understanding of the mechanisms driving e-cigarette use among hospitalized cigarette smokers (i.e., who uses e-cigarettes and what factors explain why these individuals use them). Consistent with this RFA, the contribution of e-cigarette marketing activities will be included in the novel conceptual model informed by addiction, health behavior and marketing/ communication theories that will be examined through longitudinal mediation analyses. The current proposal thus represents a critical first step toward minimizing the threat to the public health posed by e-cigarettes