Synthesis of Therapeutic Agents for Treatment of Infectious Diseases

这项工作的范围是小规模合成在体外筛查或动物试验中所需数量的化合物，以及为早期第一阶段临床研究大规模合成化合物。有些化合物需要按照cGMP规定进行合成。该合同将为合成治疗艾滋病毒、结核病、肝炎和其他与NIAID研究议程相关的传染病的有希望的化合物提供资源。

The scope of this effort is small scale synthesis of compounds in quantities required for testing in either in vitro screens or animals, and large scale synthesis of compounds for early Phase I clinical studies. Some compounds will require synthesis in compliance with cGMP regulations. This contract will provide resources for the synthesis of promising compounds for the treatment of HIV, tuberculosis, hepatitis and other infectious diseases of relevance to the research agenda of NIAID.