PRoject Implementation, Dissemination, and Evaluation (PRIDE) Core

摘要(请参阅说明)： 我们提议的卓越中心将进行三个高度相关的研究项目，以解决前列腺癌结果中的种族差异。虽然招募和保留受试者是任何类型的癌症研究的速度限制步骤，但如果要将这些研究的结果转化为实践，以减少并最终消除健康结果中的种族差异，则更迫切需要让利益相关者参与研究的进行和研究结果的传播。这种类型的利益相关者的参与对于更好地理解导致疾病流行的复杂因素集、理解自变量和因变量的背景以及在研究进行时向关键利益相关者传播研究信息是必要的 指挥。这些问题在研究中变得更加重要，这些研究旨在确定导致癌症结果种族差异的因素，并将这些信息转化为干预策略。因此，拟议的项目实施、传播和评估(PROCE)将招聘工作置于一个更大的框架中，让社区利益攸关方作为开展研究和传播研究结果过程的重要组成部分。PROCE核心的具体目标是：目标1：让社区自始至终参与中心的研究和培训方案；目标2：协助研究项目以科学严谨和社区响应的方式实现招募和执行目标；目标3： 开始向社区、政策制定者和学术利益相关者传播研究成果的过程，以便将其作为减少前列腺癌健康差异行动的基础。PROCE核心的具体活动将是：1)建立一个社区特别工作组，将参与研究项目的执行，并在研究项目完成时向社区实施翻译；2)实施试点项目资金，使社区成员和研究人员团队能够将新的研究成果转化为社区行动，以减少健康差异。 这些活动可能包括制定政策、干预措施或宣传/动员，以减少前列腺癌的差异，以及3)与培训核心建立联系，以便与社区合作伙伴和利益攸关方接触。

SUMMARY (See instructions): Our proposed Center of Excellence will conduct three highly interrelated research projects to address racial disparities in prostate cancer outcomes. While the recruitment and retention of human subjects is the rate limiting step of any type of cancer research, if findings from these studies are to be translated into practice so that racial disparities in health outcomes are reduced and ultimately eliminated, there is an even more pressing need to engage stakeholders in the conduct of studies and the dissemination of findings from the research. This type of stakeholder involvement is necessary to develop a better understanding of the complex set of factors that contribute to disease prevalence, to understand the context of independent and dependent variables, and to disseminate study information to key stakeholders as the research is being conducted. These issues become even more important in studies that are designed to identify factors that contribute to racial disparities in cancer outcomes and to translate this information into intervention strategies. For this reason, the proposed Project Implementation, Dissemination, and Evaluation (PRIDE) Core places recruitment efforts into a larger framework of involving community stakeholders as vital components of the process of conducting research and disseminating the results of studies. The specific aims of the PRIDE core are to: Aim 1: Establish community engagement in the Center's program of research and training from start to finish; Aim 2: Assist the research projects to achieve recruitment and implementation goals in a manner that is both scientifically rigorous and community-responsive; Aim 3: Begin the process of disseminating research findings to community, policymakers, and academic stakeholders in order to use them as a foundation for action to reduce prostate cancer health disparities.The specific activities of the PRIDE core will be to: 1) Establish a community task force that will be involved in the execution of the research projects, and implement translation to the community at the completion of the research projects; 2) Implement pilot project funding that will allow teams of community members and researchers to translate emerging research findings to create community action to reduce health disparities. These activities may include establishment of policies, interventions, or advocacy/mobilization to reduce prostate cancer disparities, and 3) Link to the training core to engage with community partners and stakeholders.