Research Core

该计划的总体目标是通过集中和协调的研究合作，加强佛罗里达农工大学癌症研究的研究基础设施。尽管化疗药物及其作用机制有了重大发现，但对具有新的作用机制的新化学实体的需求仍然很高，用于治疗乳腺癌和肺癌。因此，我们计划通过研究合作，积极开发新的抗癌药物/组合及其参与肿瘤消退的分子机制。乳腺癌和肺癌是影响少数民族人口的最常见癌症，因此选择这两种癌症作为FAMU的研究对象。

The overall goal of this initiative is to strengthen the research infrastructure for cancer research at Florida A&M University through research collaboration in a focused and coordinated effort. Despite significant discovery of chemotherapeutic agents and their mechanisms of action, the need for new chemical entities having new mechanisms of action for the treatment of breast and lung cancer remains high. Therefore, an aggressive exploitation of new anticancer agents/combination and their molecular mechanisms involved in tumor regression are planned through research collaboration. Breast and lung cancer are the most common cancer affecting minority populations and these two cancers hence been chosen to be pursued at FAMU. Furthermore, FAMU has researchers who are performing cutting edge research in these areas and hence can contribute in building a strong infrastructure for other researchers. Another impetus for this activity is to take a step towards remedy for the persistent disparity in the number of minority investigators involved in targeted cancer therapy research. The difficulty in implementing innovative approaches in cancer research at historically black colleges and universities is due to the lack of adequate resources, trained investigators and research infrastructure for breast and lung cancer therapy.