WirelessTechnology Assisted Weight Management in Pre-Diabetic Adolescents...

项目总结(见说明)： 超重/肥胖的患病率存在很大差异，非裔美国城市青少年和年轻人普遍受到影响。他们中的许多人形成了2型糖尿病前期的代谢安排，在没有干预的情况下，最终发展为2型糖尿病。 行为干预需要激励行为改变，减轻体重，并最终预防2型糖尿病的发展。手机短信已经显示出吸引糖尿病青年和年轻人自我监测血糖的前景。手机是便携的，广泛使用，并被青少年和年轻人接受。令人兴奋的初步证据表明，使用 具有网络功能的手机技术在成人糖尿病患者的管理中是有用的。这项拟议研究的总体目标是实施并严格评估这一成功应用于成人患者管理的创新计划在青少年中的预防益处，该计划包括最先进的通信和网络技术。为了实现这一目标，本提案的具体目标是比较使用最先进的通信和网络技术或使用Lifestyle团体访问提供的生活方式改变干预的有效性。被诊断为前期2型糖尿病的18-24岁的年轻人将被转介到霍华德大学医院糖尿病治疗中心参与这一项目。参与者将从霍华德大学医院的诊所招募，霍华德大学医院是一家为少数族裔服务的机构。符合条件的和同意的青年将被随机分到上述两个治疗组中的一个。患者活跃度的有效测量将是主要结果，并在干预后的基线、三个月、六个月和一年进行评估。将评估组内和组间的变化，并在相同的时间点监测其他生物生理结果(体重指数和血红蛋白Alc)。研究结果对解决早期健康发病率的重要差异具有重要意义。我们的分析将测试是否 推广手机技术，通过联网的PHR‘和教育门户网站获取健康信息，有望成为对有患2型糖尿病风险的非裔美国人晚期青少年/年轻人的预防性干预。

PROJECT SUMMARY (See instructions): There are significant disparities in the prevalence of overweight/obesity, with African-American urban adolescents and young adults commnonly affected. Many of them develop metabolic arrangements characteristic of pre-type 2 diabetes and, without intervention, eventually progress to type 2 diabetes. Behavioral interventions are required to motivate behavioral change, reduce weight, and eventually prevent the development of type 2 diabetes. Cell phone text messaging has already shown promise in engaging diabetic youth and young adults to self monitor their blood glucose. Cell phones are portable, widely used and accepted by adolescents and young adults. Exciting preliminary evidence is available suggesting that use of Web-enabled cell phone technology is useful in the management of adult patients with diabetes. The overall objective of the proposed study is to implement and rigorously evaluate the preventive benefits in adolescents of this innovative program successfully applied in adult patient management that includes state of- the-art communications and networking technologies. To achieve this objective, the specific aim of this proposal is to compare the effectiveness of a lifestyle change intervention delivered either using state-of-theart communications and networking technologies or using Lifestyle Group Visits. Young adults 18-24 years of age with a diagnosis of pre- type 2 diabetes will be referred to the Howard University Hospital Diabetes Treatment Center for participation in this project. Participants will be recruited from clinics at Howard University Hospital, a minority-serving institution. Eligible and consenting youth will be randomized to one of the 2 treatment groups as described above. A validated measure of patient activation will be the primary outcome, and be assessed at baseline, three months, six months and one year following intervention. Both within and between group changes will be assessed, and additional biophysiologic outcomes (body mass index and hemoglobin AlC) will also be monitored at the same time points. Study findings have significant implications in addressing an important disparity in early health morbidity. Our analyses will test whether the extension of cell phone technology with access to health information through web-enabled PHR'and educational portals yield promise as a preventive intervention among African American late adolescents/young adults at risk for type 2 diabetes.